This is an open-label, solid tumor, continuation, rollover trial which enrolls participants from ongoing BMS parent studies that evaluated adagrasib (MRTX849, BMS-986503) either as monotherapy or in combination with other cancer therapies in patients with non-small cell lung cancer (NSCLC), colorectal cancer (CRC) and other advanced solid tumors.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
170
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Number of Participants With Adverse Events (AEs)
Time frame: Up to 90 days from last dose or study discontinuation
Number of Participants With AEs Leading to Treatment Discontinuation
Time frame: Up to 90 days from last dose or study discontinuation
Number of Participants With Serious Adverse Events (SAEs)
Time frame: Up to 90 days from last dose or study discontinuation
Number of Participants With AEs Leading to Death
Time frame: Up to 90 days from last dose or study discontinuation
BMS Clinical Trials Contact Center www.BMSClinicalTrials.com
CONTACT
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CONTACT
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Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Specified dose on specified days
Local Institution - 0005
Phoenix, Arizona, United States
WITHDRAWNSouthern California Permanente Medical Group
Bellflower, California, United States
RECRUITINGMemorialCare - Long Beach Medical Center
Long Beach, California, United States
RECRUITINGLocal Institution - 0003
Newark, Delaware, United States
WITHDRAWNFlorida Cancer Specialists - North
St. Petersburg, Florida, United States
RECRUITINGCancer Center of Kansas
Wichita, Kansas, United States
RECRUITINGLocal Institution - 0092
Boston, Massachusetts, United States
WITHDRAWNDana Farber Cancer Center
Boston, Massachusetts, United States
RECRUITINGMayo Clinic in Rochester, Minnesota
Rochester, Minnesota, United States
RECRUITINGMetro-Minnesota Community Oncology Research Consortium (MMCORC)
Saint Paul, Minnesota, United States
RECRUITING...and 90 more locations