The aim of this study was to investigate the safety, tolerability, and effectiveness of eltrombopag in combination with immunosuppressive therapy (IST) in real world practice in pediatric patients with severe aplastic anemia (sAA) in Korea. The study used data over a 6-month period extracted from patients' medical charts (electronic medical records) starting from the initiation of eltrombopag treatment.
Study Type
OBSERVATIONAL
Enrollment
13
Novartis
East Hanover, New Jersey, United States
Incidence of Adverse Events (AEs) and Serious Adverse Events (SAEs)
Incidence of all AEs/adverse drug reactions (ADRs), SAEs/serious adverse drug reactions (SADRs), and unexpected AEs/ADRs.
Time frame: Up to 6 months
Overall Response Rate (ORR)
ORR includes complete response (CR) and partial response (PR). CR was defined as meeting all three of the following criteria: * Absolute neutrophil count (ANC) \> 1.0 × 10\^9/L * Platelet count \> 100 × 10\^9/L * Hemoglobin \> 100 g/L PR was defined as hematologic improvement that did not meet the criteria for CR, but also did not meet the criteria for sAA.
Time frame: 6 months
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.