To assess the real-world impact of glucose-lowering drugs (GLDs) as an adjunct to insulin in Chinese patients with type 1 diabetes (T1DM). Does glucose-lowering drugs (GLDs) as an adjunct to insulin improve clinical outcomes in Chinese patients with type 1 diabetes (T1DM) when used long-term in real-world practice?
Study Type
OBSERVATIONAL
Enrollment
500
The glucose-lowering drugs included in the analysis were metformin, acarbose and DPP-4i alone or in combination with other agents.
HbA1c
The primary outcome measure is glycated hemoglobin (HbA1c), which reflects the average blood glucose level of Chinese patients with type 1 diabetes mellitus (T1DM) over the past 2-3 months. HbA1c levels will be measured using a standardized clinical detection method at the baseline and follow-up visits of the study, to evaluate the long-term blood glucose control effect of insulin plus GLDs combined therapy compared with insulin monotherapy in real-world practice.
Time frame: Baseline to 3 months, 6 months, 12 months
Absolute and relative insulin doses
Time frame: Baseline to 3 months, 6 months, 12 months
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