Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes

Central Hospital, Nancy, France120 enrolled

Overview

The goal of this study is to build a database of personalized EP (Electrical Properties) maps (accounting for age, anatomical location, and tissue complexity), obtained via MRI, to improve electromagnetic safety assessments, especially in the context of MRI. The EP values derived from this study are expected to be more accurate than current literature values, leading to more realistic specific absorption rate (SAR) modeling and improved patient safety. To investigate age-related differences, the study will include three distinct age groups.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

OTHER

Masking

NONE

Enrollment

120

Conditions

Healthy Subjects

Interventions

Magnetic Resonance Imaging (MRI) examination

Eligibility

Sex: ALLMin age: 6 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Person aged between 6 and 12, 20 and 40 years or aged 70 years and above * Person affiliated with a social security scheme or beneficiary of such a scheme * Person, or parent/legal guardian in the case of minors, who has received full information about the organization of the study and has signed the informed consent form Exclusion Criteria: * Contraindication to undergoing an MRI examination or the presence of an MRI-incompatible medical device * Person presenting a pathology or tissue damage in the examined areas that may affect the measured MRI parameters * Pregnant woman, woman in labor, or breastfeeding mother * Person deprived of liberty by judicial or administrative decision, or persons undergoing psychiatric care

Outcomes

Primary Outcomes

Conductivity in S/m at the head level in subjects aged 6 to 12 years

Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 6 to 12 years

Time frame: Baseline (J0)

Conductivity in S/m at the head level in subjects aged 20 to 40 years

Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 20 to 40 years

Time frame: Baseline (J0)

Conductivity in S/m at the head level in subjects aged 70 and above

Measurement of conductivity (in Siemens per meter, S/m) at the head level in subjects aged 70 and above

Time frame: Baseline (J0)

Conductivity in S/m at the neck level in subjects aged 6 to 12 years

Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 6 to 12 years

Time frame: Baseline (J0)

Conductivity in S/m at the neck level in subjects aged 20 to 40 years

Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 20 to 40 years

Time frame: Baseline (J0)

Conductivity in S/m at the neck level in subjects aged 70 and above

Measurement of conductivity (in Siemens per meter, S/m) at the neck level in subjects aged 70 and above

Time frame: Baseline (J0)

Conductivity in S/m at the torso level in subjects aged 6 to 12 years

Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 6 to 12 years

Time frame: Baseline (J0)

Conductivity in S/m at the torso level in subjects aged 20 to 40 years

Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 20 to 40 years

Time frame: Baseline (J0)

Conductivity in S/m at the torso level in subjects aged 70 and above

Measurement of conductivity (in Siemens per meter, S/m) at the torso level in subjects aged 70 and above

Time frame: Baseline (J0)

Imaging of Electrical Properties by MRI: Investigation of Age-Related Changes

Overview

Conditions

Interventions

Eligibility

Locations (2)

Outcomes

Primary Outcomes

Central Contacts