Role of Saline Infusion Sonohysterography in Detection of Pelvic Adhesions in Infertile Women

Sohag University120 enrolled

Overview

Infertility is agrowing concern affecting million of couples worldwide,with infertility being asignificant subset, infertility is define as inability to achieve pregnancy after one year of regular unprotected sexual intercours Among these , pelvic Adhesions present amajor challenge in reproductive medicine as they can lead to tubal occulsion and uterine cavity distortion Saline infusion sonohysterography (SIS)has emerged as minimally invasive,cost effected,and well tolerated alternative for assessing uterine and tubal abnormalities in infertile patient SIS involve the introduction of sterile saline into the uterine cavity under ultrasound guidance ,enhancing the visualization of Endometrial lining, intrauterine abnormalities and tubal patency,compared to HSG, SIS offer several advantages including the avoidance of radiation exposure, better patient comfort and the ability to stimultaneously assess the myometrium and adenxal structure

Study Type

INTERVENTIONAL

Allocation

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

120

Conditions

Infertile Women With Pelvic Adhesions

Interventions

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * infertile women aged 18-45yr Patient suspected to have pelvic Adhesions Women with normal ovulatory function and normal husband semen analysis Exclusion Criteria: * active pelvic infection or abnormal vaginal bleeding Pt with cervical stenosis Congenital uterine mullerian anomalies Pt with pelvic malignancy

Outcomes

Primary Outcomes

Diagnostic Accuracy of saline infusion sonohysterography (SIS): sensitivity,specificity, positive predictive value(PPV) and negative predictive value (NPV) for detecting pelvic Adhesions compared to Laparoscopy in infertile women

dorsolithotomy position and Speculum insertion into vagina and catheter insetion into uterine cavity inflated with 1\_2ml of saline to secure placement with infusion of 10\_20 ml of sterile saline into uterine cavity through the catheter while performing transvaginal ultrasound imaging

Time frame: One year

Secondary Outcomes

Uterune and tubal findings: presence of tubal blockage, hydrosalpinx or peritoneal adhesions

Infusion of saline intrauterine undertransvaginal ultrasound imaging for detection of tubal block or peritoneal adhesions in infertile women