This study aims to fill the gaps regarding the effectiveness of paracetamol alone with paracetamol combined with cold sponging in febrile children.
Given the conflicting findings in existing literature, the role of cold sponging in fever management remains uncertain. Some studies suggest a transient advantage in early temperature reduction, while others highlight limited long-term benefit and increased discomfort. Therefore, this study seeks to determine whether cold sponging offers meaningful additional benefit or merely adds distress without enhancing the efficacy of paracetamol. The findings would generate evidence-based guidance for using cold sponging in febrile children.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
210
Children will receive paracetamol alone, as a single dose of paracetamol syrup (15 mg/kg) orally.
Children will receive paracetamol as a single dose of paracetamol syrup (15 mg/kg) orally, and cold sponging will be performed immediately following paracetamol administration for 15 minutes, using room-temperature water (approximately 25°C) to sponge the forehead, arms, and legs.
Dr. Ruth KM Pfau Civil Hospital, Karachi, Dow University of Health Sciences
Karachi, Sindh, Pakistan
Fever reduction
Achievement of a temperature \<38°C within 60 minutes will be considered as the reduction in fever and effectiveness of the treatment.
Time frame: 60 minutes
Change in heart rate
The change in the heart rate will be compared between the two groups.
Time frame: 60 minutes
Change in respiratory rate
The change in the respiratory rate will be compared between the two groups.
Time frame: 60 minutes
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