Interest in identifying low GI foods and the food factors responsible for the low GI of foods has increased. Three corn products with varying levels of refined and whole grain corn will be compared to each other and to a dextrose control. It is hypothesized that higher levels of whole grain corn present in a food will decrease the rate of absorption and result in a lower postprandial glucose levels and glycemic index, and that the whole grain ingredient manufacturing process impacts whole grain ingredient benefits.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
QUADRUPLE
Enrollment
29
Varying amounts of whole-grain corn from none to some to more
A solution containing 25g of available carbohydrates on 2 separate occasions
INQUIS Clinical Research
Toronto, Ontario, Canada
iAUC (incremental area under the curve)
Compare the plasma glucose in mmol/L of three corn products
Time frame: Change from fasting baseline (-5 minutes and 0 minutes) to 15, 30, 45, 60, 90 and 120 minutes after test snack consumed within 10 minutes
Glycemic Index (GI)
Compare the plasma glucose in mmol/L of three products with varying levels of refined and whole grain corn vs. dextrose control
Time frame: Change from fasting baseline (-5 minutes and 0 minutes) to 15, 30, 45, 60, 90 and 120 minutes after test snack consumed within 10 minutes
Glycemic load (GL)
Calculate the GI x (grams available carbohydrate in a serving) where a serving is 28 grams of each of the three corn products
Time frame: Change from fasting baseline (-5 minutes and 0 minutes) to 15, 30, 45, 60, 90 and 120 minutes after test snack consumed within 10 minutes
Incremental glucose levels
Compare glucose levels in mmol/L at individual timepoints after each of three corn products
Time frame: Change from fasting baseline (-5 minutes and 0 minutes) to 15, 30, 45, 60, 90 and 120 minutes after test corn snack consumed within 10 minutes
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.