Evaluation of MUSA-3 in Microsurgical Anastomoses

Inclusion Criteria: * Patient age ≥ 18 years. * Patients requiring procedures involving micro-anastomosis of small anatomical structures-such as blood vessels, nerves, or lymphatic vessels-in free flap, lymphatic, or peripheral nerve surgery. * Patients who have been selected by the research team at the Clinical Center as appropriate candidates for treatment with MUSA-3 in accordance with the IFU. * Able to give informed consent before participating in the study. * Provision of signed and dated informed consent form. Exclusion Criteria: * Subject participates in a potentially confounding drug or device trial during the course of the study. * Patients that are pregnant or breastfeeding. For Lymphedema patients: * ≥ISL (International Society of Lymphology) Stage III lymphedema * History of marcaine or indocyanine green allergy * Non-viable lymphatic system as determined by ICG lymphatic mapping using near infrared camera