Cross-sectional Study of Vitamin B6 in Parkinson's Disease

University of Rochester288 enrolled

Overview

The purpose of this study is to estimate the prevalence of abnormal serum levels of vitamin B6, and the associations of those levels with demographic and clinical variables in a randomly selected sample of people living with Parkinson's disease, compared to historical controls.

Study Type

OBSERVATIONAL

Enrollment

288

Conditions

Parkinson's Disease (PD)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * People with a clinical diagnosis of Parkinson's disease according to the diagnostic criteria of the Movement Disorders Society \[Postuma 2015\]. * Participants are ≥ 18 years old. * As determined by the study investigators, participants are able to communicate at a level sufficient to undergo study interviews. * As determined by the study investigators, participants have the capacity to provide written informed consent and the ability to comply with all study procedures. Exclusion Criteria: * People expected to have abnormal vitamin B6 levels due to underlying conditions (renal disease, bowel disease, rheumatoid arthritis). * People taking medications (other than levodopa) expected to interfere with B6 levels (steroids, cycloserine, hydralazine, isoniazid, theophylline, penicillamine).

Locations (1)

Movement Disorders Clinic, University of Rochester Medical Center

Rochester, New York, United States

Outcomes

Primary Outcomes

Serum levels of vitamin B6 (Fasting)

nmol/L (log-transformed)

Time frame: At enrollment

Secondary Outcomes

Age

Years

Time frame: At enrollment

Sex

Female/Male

Time frame: At enrollment

Race

As defined by the U.S. Office of Management and Budget: American Indian or Alaska Native, Asian, Black or African American, Native Hawaiian or Other Pacific Islander, White

Time frame: At enrollment

Ethnicity

As defined by the U.S. Office of Management and Budget: Hispanic or Latino, non-Hispanic or Latino

Time frame: At enrollment

Body mass index

kg/m2

Time frame: At enrollment

Diabetes

Yes/No

Time frame: At enrollment

Smoking

Yes/No

Time frame: At enrollment

Alcohol use

Yes/No

Time frame: At enrollment

Daily consumption of protein in the last 30 days

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.