Topical Insulin Dressing on Management of Diabetic Foot Ulcers

Inclusion Criteria: * Patients with diabetes between the age group 18-85 years. * Both sexes. * Patients who were diagnosed with diabetic foot according to the 2010 Edition of the Clinical Practice Guidelines for the Prevention and Management of Diabetes Foot Complications (edited by the American Diabetes Association) presented to diabetic foot clinic on regular basis. * Participants who were able to and willing to participate in the study voluntarily who could come for dressings on a daily basis, or patients who agreed for admission for the duration of treatment were included in the study. * Patients having ulcer below the ankle on the dorsal or plantar aspect of the foot. * Patients with grade I and grade II ulcers of Wegener's Classification without significant growth of granulation tissue. * Patients with controlled blood glucose levels between 110 and 130 gm/dl. Hemoglobin A1c was 7.1 ± 0.34. * Non heavely infected wounds without significant growth of granulation tissue. Exclusion Criteria: * Patients with diabetic foot ulcers of Wagner grade V. * X-ray showing features of osteomyelitis. * Duplex showing significant atherosclerotic changes and venous abnormalities like varicosities. * Malnutrition and uncontrolled diabetes mellitus. * Other clinically significant medical conditions that would impair wound healing like any hepatic, renal, immunological and neurological disease and coagulopathy. * Patients receiving corticosteroids, other immunosuppressive agents, radiation or chemotherapy one month prior to entry into the study.