CHEST-CA: Study of Chest Pain and Hidden Cardiac Amyloidosis

Rigshospitalet, Denmark300 enrolled

Overview

The objective of this observational, prospective study is to determine the prevalence of Cardiac Amyloidosis (CA) in males over the age of 65 who experience chest pain but show no signs of coronary artery disease (CAD). Prior to inclusion, all patients will have undergone a CT coronary angiogram or an Rb-PET scan to rule out the possibility of CAD. Participants will be subject to several examinations, including blood tests, urine samples, ECG, echocardiography, and bone scintigraphy. An endomyocardial biopsy may be conducted if necessary.

Study Type

INTERVENTIONAL

Allocation

Purpose

SCREENING

Masking

NONE

Enrollment

300

Conditions

Cardiac Amyloidosis Chest Pain

Interventions

Clinical examination, blood samples, echo, bone scintigraphy

Eligibility

Sex: MALEMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: No signs of CAD through Rb-PET and/or CT coronary arteriogram Exclusion Criteria: Previous history of amyloidosis

Locations (1)

Rigshospitalet

Copenhagen, Denmark

RECRUITING

Outcomes

Primary Outcomes

Prevalence of ATTR-CA in patients experiencing chest pain

Time frame: Up to 4 weeks

Central Contacts

Navid Noory, MD

CONTACT

4535453108 navid.noory@regionh.dk

Data from ClinicalTrials.gov

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