This prospective, single-arm interventional study aims to evaluate the effectiveness of a structured postoperative pulmonary physiotherapy program delivered by the research team in patients undergoing lung cancer surgery. The intervention consists of chest physiotherapy, bronchial hygiene techniques, early mobilization, and postural exercises applied under physiotherapist supervision during the postoperative hospital stay. The primary outcome is length of hospital stay. Secondary outcomes include blood pressure, heart rate, oxygen saturation, fatigue, and dyspnea levels. Clinical outcomes will be analyzed according to age groups (45-59 years and 60-90 years) to determine potential age-related differences in response to the intervention.
This interventional study aims to evaluate the effectiveness of a structured pulmonary physiotherapy program applied after lung cancer surgery across different age groups. Patients aged 45 years and older undergoing lung resection will be included and categorized into two age groups (45-60 years and ≥60 years) for subgroup analysis. The structured postoperative pulmonary physiotherapy program is initiated in the early postoperative period and continued until hospital discharge. The program includes chest physiotherapy techniques, early mobilization, postural exercises, and incentive spirometry training. The intervention is delivered once daily under physiotherapist supervision, and participants are instructed to continue prescribed breathing, incentive spirometry, and mobilization exercises independently during the afternoon and evening sessions. The primary outcome measure is length of hospital stay. Secondary outcomes include postoperative pain assessed by Visual Analog Scale (VAS), dyspnea and fatigue assessed by Borg scale, oxygen saturation, hemodynamic parameters, and inflammatory and biochemical markers including C-reactive protein (CRP), neutrophil-to-lymphocyte ratio (NLR), albumin, prealbumin, creatine kinase (CK), and lactate dehydrogenase (LDH). Clinical, physiological, and biochemical outcomes are assessed from the early postoperative period until hospital discharge. The study further aims to explore potential differences in treatment response between predefined age groups. No randomization or control group is included, as all participants receive the same structured physiotherapy intervention.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
Enrollment
60
The structured postoperative pulmonary physiotherapy program is delivered by the research team during the hospital stay following lung cancer surgery. The intervention is applied according to a standardized protocol and includes supervised chest physiotherapy techniques (deep breathing exercises, thoracic expansion exercises, airway clearance techniques, and incentive spirometry), early mobilization (progressive sitting, standing, and ambulation), and postural exercises. The program is administered once daily under physiotherapist supervision. In addition, participants are instructed to continue the prescribed breathing, incentive spirometry, and mobilization exercises independently during the afternoon and evening sessions. The intervention is initiated in the early postoperative period and continues until hospital discharge.
Bezmialem Vakif University
Istanbul, Turkey (Türkiye)
Length of Hospital Stay
Length of hospital stay is defined as the number of days from postoperative admission to the ward until hospital discharge following lung cancer surgery.
Time frame: Postoperative period, from ward admission after surgery until hospital discharge (maximum 30 postoperative days)
C-reactive protein (CRP)
Serum CRP levels (mg/L) will be measured to evaluate postoperative systemic inflammatory response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Peripheral Oxygen Saturation (SpO₂)
Peripheral oxygen saturation (%) will be measured using pulse oximetry to assess postoperative oxygenation status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Neutrophil-to-Lymphocyte Ratio (NLR)
NLR will be calculated from complete blood count parameters to assess systemic inflammatory status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Serum Albumin
Serum albumin levels (g/dL) will be measured to assess nutritional status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Systolic Blood Pressure
Systolic blood pressure (mmHg) will be recorded to assess postoperative hemodynamic response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Diastolic Blood Pressure
Diastolic blood pressure (mmHg) will be recorded to assess postoperative hemodynamic response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Heart Rate
Heart rate (beats per minute) will be measured to evaluate cardiovascular response during the postoperative period.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Dyspnea Severity
Dyspnea severity will be assessed using the Modified Borg Dyspnea Scale (0-10), where 0 indicates "no breathlessness" and 10 indicates "maximal breathlessness."
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Fatigue Severity
Fatigue will be assessed using the Borg Rating of Perceived Exertion (0-10), where higher scores indicate greater perceived fatigue.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Incisional Pain Intensity
Incisional pain will be evaluated using the Numeric Rating Scale (NRS, 0-10), where 0 represents "no pain" and 10 represents "worst imaginable pain."
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
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