This ambispective observational cohort study aims to evaluate age-related differences in clinical outcomes among patients undergoing lung cancer surgery who received a structured comprehensive in-patient physiotherapy (CIPT) program as part of standard postoperative care. The CIPT program includes patient education, chest physiotherapy, breathing exercises, airway clearance techniques, early mobilization, postural exercises, and upper- and lower-extremity range-of-motion exercises during the postoperative hospital stay. The primary outcome is hospital length of stay. Secondary outcomes include clinical parameters (blood pressure, resting heart rate, oxygen saturation, and respiratory rate), symptom-related outcomes (dyspnea, fatigue, and incisional pain), and inflammatory biomarkers (C-reactive protein, neutrophil-to-lymphocyte ratio, and albumin). Outcomes are analyzed according to predefined age groups (45-64 years and 65-90 years) to evaluate potential age-related differences.
This ambispective observational cohort study evaluates age-related differences in clinical outcomes among patients undergoing lung cancer surgery who received a structured comprehensive in-patient physiotherapy (CIPT) program as part of standard postoperative care. Patients aged 45-90 years were included and classified into two predefined age groups: middle-aged (45-64 years) and older (65-90 years). The CIPT program was initiated on the first day after transfer from the intensive care unit to the thoracic surgery ward and continued until hospital discharge. The program included patient education, breathing exercises, incentive spirometry, airway clearance techniques, early mobilization, postural exercises, and upper- and lower-extremity range-of-motion exercises. One session per day was supervised by a physiotherapist, with additional sessions performed independently by the patient or with caregiver assistance during hospitalization. The primary outcome was hospital length of stay. Secondary outcomes included clinical parameters (blood pressure, resting heart rate, oxygen saturation, and respiratory rate), symptom-related outcomes (dyspnea, fatigue, and incisional pain), and inflammatory biomarkers (C-reactive protein \[CRP\], neutrophil-to-lymphocyte ratio \[NLR\], and albumin). Outcomes were assessed during the postoperative inpatient period and compared between the predefined age groups. No randomization or non-intervention control group was included, as all participants received the same structured CIPT program as part of standard postoperative care.
Study Type
OBSERVATIONAL
Enrollment
60
The comprehensive in-patient physiotherapy (CIPT) program was provided as part of standard postoperative care following lung cancer surgery. The program included patient education, breathing exercises, incentive spirometry, airway clearance techniques, early mobilization, postural exercises, and upper- and lower-extremity range-of-motion exercises. It was initiated on the first day after transfer to the thoracic surgery ward and continued until hospital discharge. One session per day was supervised by a physiotherapist, with two additional sessions performed independently by the patient or with caregiver assistance
Bezmialem Vakif University
Istanbul, Turkey (Türkiye)
Length of Hospital Stay
Length of hospital stay is defined as the number of days from postoperative admission to the ward until hospital discharge following lung cancer surgery.
Time frame: Postoperative period, from ward admission after surgery until hospital discharge (maximum 30 postoperative days)
C-reactive protein (CRP)
Serum CRP levels (mg/L) will be measured to evaluate postoperative systemic inflammatory response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Peripheral Oxygen Saturation (SpO₂)
Peripheral oxygen saturation (%) will be measured using pulse oximetry to assess postoperative oxygenation status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Neutrophil-to-Lymphocyte Ratio (NLR)
NLR will be calculated from complete blood count parameters to assess systemic inflammatory status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Serum Albumin
Serum albumin levels (g/dL) will be measured to assess nutritional status.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Systolic Blood Pressure
Systolic blood pressure (mmHg) will be recorded to assess postoperative hemodynamic response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Diastolic Blood Pressure
Diastolic blood pressure (mmHg) will be recorded to assess postoperative hemodynamic response.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Heart Rate
Heart rate (beats per minute) will be measured to evaluate cardiovascular response during the postoperative period.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Dyspnea Severity
Dyspnea severity will be assessed using the Modified Borg Dyspnea Scale (0-10), where 0 indicates "no breathlessness" and 10 indicates "maximal breathlessness."
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Fatigue Severity
Fatigue will be assessed using the Borg Rating of Perceived Exertion (0-10), where higher scores indicate greater perceived fatigue.
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
Incisional Pain Intensity
Incisional pain will be evaluated using the Numeric Rating Scale (NRS, 0-10), where 0 represents "no pain" and 10 represents "worst imaginable pain."
Time frame: Postoperative Day 1 and at hospital discharge (up to 30 days after surgery)
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