The goal of this clinical trial is to learn if a new toothpaste can prevent enamel erosion in healthy adults. Researchers will compare the test toothpaste to a control toothpaste to see if there is a difference in erosion levels. Participants will brush twice a day for two minutes with their assigned toothpaste.
The objective of this clinical study is to assess the efficacy of New Toothpaste Containing SnF as compared to commercially available toothpaste in the reduction of enamel erosion over a ten (10) days period. This investigation will be a randomized, double-blinded, single-center, parallel clinical study. Subjects will be randomly assigned to one of the two study groups, and will be instructed to use their assigned toothpaste for a period of ten (10) days.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
80
Participants will brush with a new toothpaste containing SnF for two minutes twice daily.
Participants will brush with a regular fluoride toothpaste twice daily for two minutes.
School of Dentistry, University of Texas Health San Antonio
San Antonio, Texas, United States
Surface loss
Depth of surface loss in an enamel block worn on a dental retainer by the participant, as determined by an optical profilometer.
Time frame: From baseline to the end of treatment at 10 days.
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