This study evaluated whether a rehabilitation program performed during hemodialysis sessions could improve daily functioning and mobility in adults receiving maintenance hemodialysis. Participants took part in either exercise-based rehabilitation, breathing muscle training, or usual care. The study compared changes in functional independence and mobility before and after the rehabilitation period.
This academic clinical study was conducted in two dialysis centers in Istanbul between June 2016 and March 2017. Adults undergoing maintenance hemodialysis were allocated to one of three groups: dynamic lumbar stabilization exercises, inspiratory muscle training, or a control group receiving routine nephrological care. Participants in the intervention groups completed a supervised intradialytic rehabilitation program three times per week for 10 weeks. Functional independence and mobility-related performance were assessed at baseline and after completion of the intervention using validated functional assessment measures. The study was conducted as part of a doctoral thesis and is being retrospectively registered for transparency.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
56
A structured intradialytic exercise program focusing on trunk stabilization and neuromuscular control, performed under supervision during hemodialysis sessions.
Respiratory muscle training performed during hemodialysis using threshold-based breathing exercises under supervision.
Six-Minute Walk Test
Functional exercise capacity assessed as the distance walked in six minutes, measured according to standardized procedures.
Time frame: Baseline and after 10 weeks
Timed Up and Go Test (TUG)
Functional mobility assessed by the time required to stand up from a chair, walk three meters, turn, walk back, and sit down.
Time frame: Baseline and after 10 weeks
Five Times Sit-to-Stand Test (5STS)
Lower extremity functional performance assessed as the time required to complete five consecutive sit-to-stand movements.
Time frame: Baseline and after 10 weeks
Maximal Inspiratory Pressure (MIP)
Inspiratory muscle strength measured as maximal inspiratory pressure using standardized respiratory pressure measurement techniques.
Time frame: Baseline and after 10 weeks
Maximal Expiratory Pressure (MEP)
Expiratory muscle strength measured as maximal expiratory pressure using standardized respiratory pressure measurement techniques.
Time frame: Baseline and after 10 weeks
Forced Vital Capacity (FVC)
Pulmonary function assessed as forced vital capacity measured by spirometry according to standard guidelines.
Time frame: Baseline and after 10 weeks
Forced Expiratory Volume in 1 Second (FEV1)
Pulmonary function assessed as forced expiratory volume in one second measured by spirometry according to standard guidelines.
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Time frame: Baseline and after 10 weeks