Prevalence of Treponema Parvum in Subgingival Microbiome of Patients With Periodontitis

University of Baghdad112 enrolled

Overview

The current study primarily aims to evaluate the presence of T. parvum in periodontal health and disease, and its correlation with clinical parameters. Subgingival plaque samples will be collected using sterile paper points then the samples will be analyzed using quantitative polymerase chain reaction (qPCR) to detect T. parvum and estimate its relative amount in the biofilm. The results may help clarify the association between T. parvum and periodontitis.

Study Type

OBSERVATIONAL

Enrollment

112

Conditions

Periodontitis

Eligibility

Sex: ALLMin age: 30 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: include participants who have at least 20 teeth and diagnosed as generalized periodontitis. Exclusion Criteria: participants meeting any of the following criteria were excluded: (1) undergoing orthodontic treatment; (2) having a history of antibiotic/nonsteroidal anti-inflammatory drugs use within the last three months; (3) having a history of valve replacement who need prophylactic antibiotic coverage; (4) pregnant or lactating women; (5) having a history periodontal therapy within the last six month. \-

Locations (1)

College of Dentistry, University of Baghdad

Baghdad, Iraq

RECRUITING

Outcomes

Primary Outcomes

Relative abundance of T. parvum in subgingival biofilm

Detection and relative abundance of T. parvum in subgingival biofilm measured by qPCR from subgingival plaque collected using sterile paper points

Time frame: At enrollment

Central Contacts

Mays Jaafar Dentist, B.D.S

CONTACT

009647712910127 mays.allah2405@codental.uobaghdad.edu.iq

Data from ClinicalTrials.gov

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