Comparison of Rate and Amount of Orthodontic Space Closure

Dow University of Health Sciences34 enrolled

Overview

The goal of this clinical trial is to compare rate and amount of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction Primary outcome measure is to calculate rate and amount of space closure between fresh vs healed as well as maxilla and mandible.

The mandibular and maxillary arches of 34 patients will be included whose treatment plan decision was the extraction of all first premolars. Due to the split mouth approach, patients' maxillary and mandibular arches are randomly subdivided into two groups (right and left sides). First premolar extraction spaces in Group 1 will be closed once they have healed (6 week), while first premolar extraction spaces in Group 2 will be closed immediately after extraction. Both the upper and lower extraction spaces will be closed using coil springs (magnitude of force 30g per side). We'll specify the following time intervals: T1: Immediately prior to space closure; T2: 1 month after initial space closure; T3: 2 months after initial space closure T3: 3 months after initial space closure. Records will include measuring the rate and amount of space closure through Vernier calipers on dental cast as well as intraorally and will be evaluated at each time point.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Orthodontic Extraction

Interventions

Space ClosurePROCEDURE

Space Closure in fresh vs healed extraction socket

Eligibility

Sex: ALLMin age: 18 YearsMax age: 35 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients aged 18-35 years. * Patients undergoing fixed appliance treatment. * Good oral hygiene and periodontal support. * Patients with all first premolar's extraction treatment plan. * Atraumatic extraction. Exclusion Criteria: * History of previous orthodontic treatment * Systemic diseases like diabetes, hypertension etc * Any bone pathology or taking medicines like bisphosphonates * Patients with clefts or any syndromic condition. * Patients with old extraction socket.

Locations (1)

Dr Ishrat ul Ebad Khan Institute of Oral Health Sciences

Karachi, Sindh, Pakistan

Outcomes

Primary Outcomes

To compare rate of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction.

This study will be useful in making the timely decision for extraction of premolars and estimation of orthodontic treatment duration as well.

Time frame: four time points are taken. T0: Baseline, T1: One month, T2: Two months, T3: Three months

Secondary Outcomes

To compare amount of space closure among fresh vs healed extraction sites during fixed orthodontic treatment in patients with all first premolar's extraction.

Total space closure

Time frame: Space closure at T3 is subtracted from T0

Data from ClinicalTrials.gov

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