The goal of this observational study is to develop and validate a high-precision AI diagnostic model for cranial diseases by integrating clinical knowledge systems (pathophysiological classification, age stratification, and anatomical localization) to simulate radiologists' diagnostic thinking. The main question it aims to answer is: Does the AI model improve diagnostic accuracy and consistency across different hospital levels, physician qualifications, and clinical scenarios compared to traditional diagnosis? Participants' cranial MRI data (including T1, T2, FLAIR, DWI sequences) and clinical information will be collected retrospectively (2015-2025) and prospectively (2026) to train and validate the model, which will be evaluated through performance metrics (accuracy, sensitivity, specificity) and clinical efficacy assessments (doctor vs. model, with/without model assistance). This study will establish a new paradigm for clinical AI implementation, providing methodological support for precision diagnosis of neurological diseases.
Study Type
OBSERVATIONAL
Enrollment
1,000
Tongji Hospital
Wuhan, Hubei, China
RECRUITINGDiagnostic accuracy of AI model (sensitivity, specificity, AUC)
The primary outcome is the diagnostic performance of the AI model, including sensitivity, specificity, and area under the ROC curve (AUC), compared to the gold standard (e.g., histopathology or clinical diagnosis).
Time frame: Within 1 month of image acquisition
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