In the context of therapy for Borderline Personality Disorder, our department had conduct a study titled "The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy in Patients with Borderline Personality Disorder: A Study of Therapeutic Alliance, Depression, Cognitive Function, Impulsivity, Suicide Risk, BDNF Levels, NFkB Levels, SOD Levels."
Psychotherapy for Borderline Personality Disorder provided weekly for 13 weeks. Patients have given a logbooks. Researchers monitored patients weekly by telephone and monitor them during outpatient visits in the second, fourth, sixth, eighth, and twelfth weeks. Blood samples were taken before and 13 weeks after treatment. During the study, patients were advised not to consume any medications or herbal remedies outside of those prescribed by the doctor and recorded in the study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
66
13 weeks, one session per week. Each week, one 2-hour dialectical therapy group session for 5 patients in a group.
13 weeks, one session per week. Each week, one 30-minute session of individual supportive psychotherapy
Medical Faculty Diponegoro University
Semarang, Central Java, Indonesia
Therapeutic Alliances with California Psychotherapy Alliance Scales (CALPAS)
California Psychotherapy Alliance Scales (CALPAS) score. A higher CALPAS (California Psychotherapy Alliance Scale) score indicates a stronger, more positive therapeutic alliance between a patient and their therapist. The California Psychotherapy Alliance Scale (CALPAS) uses a 7-point Likert scale for its 24 items, ranging from 1 ("not at all") to 7 ("very much so"). Minimum score 24 and maximum score 168.
Time frame: 13 weeks
Depression with GRID Hamilton Depression Rating Scale (GRID HAM-D)
GRID Hamilton Depression Rating Scale (GRID HAM-D) score, interval, higher total scores indicating greater severity of depression. Minimum Score: 0 (No depression) Maximum Score: 52 (Severe depression)
Time frame: 13 weeks
cognitive function with Montreal Cognitive Assesment versi Indonesia (MoCA-Ina)
Montreal Cognitive Assesment Indonesian version (MoCA-Ina) score, interval. A 30-point screening tool validated to detect mild cognitive impairment (MCI) and dementia in Indonesia, with a score of 26 or higher considered normal.
Time frame: 13 weeks
impulsivity with Barrat Impulsiveness Scale (BIS11)
Barrat Impulsiveness Scale (BIS11) score, interval, Higher scores indicate greater impulsivity, with 30-51 indicating low, 52-71 average, and 72+ high impulsivity.
Time frame: 13 weeks
Suicide Risk with Columbia Suicide Severity Rating Scale (CSSRS)
Columbia Suicide Severity Rating Scale (CSSRS) score, interval, Any "Yes" answer to behavior or ideation requires further clinical assessment.
Time frame: 13 weeks
NFkB Levels in ng/ml
ratio scale, nanogram/mililiter
Time frame: 13 weeks
BDNF level in pg/ml
BDNF level in picogram/mililiter, ratio scale
Time frame: 13 weeks
SOD levels in ng/ml
ratio scale, nanogram/mililiter
Time frame: 13 weeks
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