The goal of this pilot randomized controlled trial is to evaluate the trial feasibility and acceptability of LLM-based chatbot for reducing alcohol use among patients with metabolic alcohol-related liver disease. Specific objectives include: 1. To assess how many MetALD patients accept the invitation to participate in the trial 2. To assess the retention rate of the participants through 3 and 6 months after treatment initiation 3. To assess the acceptability of the LLM-based chatbot in terms of participants' compliance and usability rating 4. To estimate the intervention effect on alcohol reduction 5. To explore the participants' perception and experiences in the chatbot
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
50
Over the three months following randomisation, an LLM-based chatbot will interact with each participant individually to deliver four personalized sessions of alcohol reduction information and advice, and participants will also be allowed to contact the chatbot at any time.
Over the three months following randomisation, a trained counsellor will conduct four individual daytime telephone sessions with each participant to provide personalised information and advice on reducing alcohol consumption.
Brief counselling (5 to 10 mins) to reduce drinking and a self-help booklet
Hong Kong Queen Mary Hospital
Hong Kong, Hong Kong
RECRUITINGRecruitment rate
Number of participants divided by the number of eligible subjects
Time frame: Through recruitment completion, about 12 months
Retention rate
Number of participants completed the follow-up divided by the number of participants
Time frame: 6 months after randomisation
Weekly alcohol consumption
Assessed by questions 1 and 2 of AUDIT-C
Time frame: 3 months after randomisation
Eligibility rate
Number of eligible patients divided by the number of patients screened
Time frame: Through recruitment completion, about 12 months
Weekly alcohol consumption
Assessed by questions 1 and 2 of AUDIT-C
Time frame: 6 months after randomisation
Frequency of binge drinking in the past 30 days
Self-reported
Time frame: 3 months after randomisation
Frequency of binge drinking in the past 30 days
Self-reported
Time frame: 6 months after randomisation
Frequency of heavy drinking in the past 30 days
Self-reported
Time frame: 3 months after randomisation
Frequency of heavy drinking in the past 30 days
Self-reported
Time frame: 6 months after randomisation
AUDIT score and level
Assessed by the Alcohol Use Disorders Identification Test
Time frame: 3 months after randomisation
AUDIT score and level
Assessed by the Alcohol Use Disorders Identification Test
Time frame: 6 months after randomisation
Planned drinking in the coming 30 days
Self-reported
Time frame: 3 months after randomisation
Planned drinking in the coming 30 days
Self-reported
Time frame: 6 months after randomisation
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