Objectives: To investigate the effectiveness of a telephone-based acceptance and commitment therapy (ACT) in assisting young adult drinkers with hazardous or harmful alcohol use (HH drinkers) to quit drinking. Hypothesis to be tested: Primary hypothesis: 1) those who receive telephone-based ACT will report a significantly higher biochemical validated abstinence than the control groups. Secondary hypotheses are that compared with the control groups, those who receive telephone-based ACT will show: 2) significantly higher self-reported 30-day abstinence, 3) significantly greater reduction in drinking, and 4) significantly higher psychological flexibility. Design and subjects: A Hong Kong randomized controlled trial with 2-arm waitlist controlled trial design on 288 individuals (aged 18-35 years, able to read Chinese and speak Cantonese, and with AUDIT scores≥8). Study instruments: Biochemical-validated abstinence (Urine strips), timeline Follow-Back questionnaire, self-reported 30-day abstinence and Personalized Psychological Flexibility Index, Short-Form 6 Dimensions and semi-structured interviews. Interventions: The intervention group(n=144) will receive 6-weekly telephone-based ACT. The waitlist control group (n=144) will receive 6-weekly telephone-based social support intervention. Main outcome measures: Primary outcome is biochemical-validated abstinence at the 6-month follow-up. Secondary outcomes include self-reported 30-day abstinence alcohol reduction, and psychological flexibility at baseline, post-program, 1-, 3-, and 6-month follow-ups. Data analysis: Descriptive statistics, generalized estimating equations, multiple imputation, intention-to-treat, per protocol analyses, and cost-effectiveness analysis. Expected results: The telephone-based ACT is effective in assisting HH drinkers to quit drinking.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
288
Each participant will join a six-session weekly telephone-based ACT programme conducted by the interventionists. Each session will last approximately 45-60 minutes.
Participants will receive weekly 45-minute telephone-based social support from an interventionist(not involved in the intervention group) for 6 weeks, which mimics the time and attention received by those in the intervention group.
biochemically-validated abstinence
The urine strips will be used for testing the content of ethyl glucuronide(a by-product of alcohol). Participants who self-report quitting drinking within the past 30 days at the 6-month follow-up will be invited to do the test.
Time frame: at the 6-month follow-up
self-reported 30-day alcohol abstinence
Time frame: at post-programme(T1) and at the 1-month(T2), 3-month(T3) and 6-month(T4) follow-ups
self-reported 30-day reduction in alcohol consumption
reduction in alcohol consumption refer to: 50% or more reduction in average alcohol consumption per day when compared with baseline at T0
Time frame: at post-programme(T1) and at the 1-month(T2), 3-month(T3) and 6-month(T4) follow-ups
psychological flexibility
Personalised Psychological Flexibility Index(PPFI) will be used to measure psychological flexibility by 19 items rating on a 7-point scale. Higher scores represent greater psychological flexibility. It has been validated among Chinese college students.
Time frame: at post-programme(T1) and at the 1-month(T2), 3-month(T3) and 6-month(T4) follow-ups
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.