Research on Real-time Proton Therapy Guidance Through Monitoring Proton Range Using All-digital PET

N/AActive Not RecruitingNCT07450560

Shuanghu Yuan30 enrolled

Overview

The energy transport process of proton beams after entering biological tissue is observed online via proton knife fully digital PET. The dynamic changes of the delivered dose and action range of proton beams in biological tissue are analyzed, the proton dose distribution is reconstructed, and the energy and position of the targeted ablation by proton beams are determined, so as to realize in-beam online PET monitoring for proton therapy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Solid Tumor

Interventions

proton therapyRADIATION

proton therapy

Eligibility

Sex: ALLMin age: 18 YearsMax age: 85 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients with solid tumors scheduled to receive proton therapy, with measurable lesions; 2. Signed the informed consent form. Exclusion Criteria: 1. Patients with a history of radioactive seed implantation; 2. Patients who cannot understand the purpose of treatment or are unwilling/unable to sign the informed consent form;

Locations (1)

Anhui Provincial Hospital

Hefei, Anhui, China

Outcomes

Primary Outcomes

the trajectory and range of the proton beam within the human body

the three-dimensional dynamic distribution of positron nuclides generated by proton beam irradiation

Time frame: 1 day

Data from ClinicalTrials.gov

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