Prospective Evaluation of Upright Versus Supine CT Myelography of the Lumbar Spine

N/ANot Yet RecruitingNCT07456137

University of Kansas Medical Center20 enrolled

Overview

The purpose of this prospective study is to compare the diagnostic utility of standing (upright, weight-bearing) CT myelography with standard supine CT myelography for the evaluation of lumbar central canal and neural foraminal stenoses. This study aims to determine whether upright positioning provides additional diagnostic information in patients unable to undergo MRI, with the goal of improving assessment and management of degenerative lumbar spine disease.

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Lumbar Central Canal Stenoses Neural Foraminal Stenoses

Interventions

Upright CTRADIATION

Upright CT Myelography

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age ≥ 18 years * Outpatient status * Scheduled for routine supine CT myelography Exclusion Criteria: * Inpatient status * Prior lumbar spine surgical intervention or presence of metallic lumbar spinal hardware (thoracic or cervical spinal procedures are permitted) * History of osseous metastatic disease involving the lumbar spine * Acute traumatic injury involving the lumbar spine * Pregnancy * Participant body habitus exceeding the scanner's safe operational limits (e.g., gantry/bore size clearance, table weight capacity) as defined by the device manufacturer. * Inability to tolerate CT scanning (e.g., severe pain, unable to stand independently for an extended period)

Outcomes

Primary Outcomes

Does upright CT imaging change management plans for patients with lumbar spinal stenosis

To determine whether upright CT imaging changes the management plan (yes or no) for patients with lumbar spinal stenosis.

Time frame: 1 week

Secondary Outcomes

Spine measurements

Objective measurements at different angles (mm) will be taken of the spine.

Time frame: 1 day

Severity grading of central canal stenosis

Severity grading (mild, moderate, severe) of central canal stenosis in the spine.

Time frame: 1 day

Severity grading of neural foraminal stenosis

Severity grading (mild, moderate, severe) of neural foraminal stenosis in the spine.

Time frame: 1 day

Presence or absence of nerve root compression

Presence or absence of nerve root compression in the spine.

Time frame: 1 day

Presence or absence of disc bulges

Presence or absence of disc bulges in the spine.

Time frame: 1 day

Presence or absence of herniations

Presence or absence of herniations in the spine.

Time frame: 1 day

Data from ClinicalTrials.gov

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