MAGNESIUM & SSRI VS SSRI ALONE AMONG PATIENTS OF MAJOR DEPRESSIVE DISORDER

Phase 2Active Not RecruitingNCT07458022

University of Child Health Sciences and Children's Hospital, Lahore50 enrolled

Overview

Role of Magnesium in Depressive Disorder

Because of the significant role that magnesium serves in mood regulation, the goal of this study is to evaluate the impact of starting the therapy of major depressive disorder with a combination of SSRI and Mg, as well as SSRI alone.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Major Depressive Diorder

Interventions

Use of magnesium with SSRIDRUG

Impact of combination of SSRI and Magnesium in Major Depressive Disorder

SSRIDRUG

Only SSRI will be given

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: All patients of above 18 years diagnosed with DSM who had MDD and receiving SSRI alone and SSRI plus magnesium. Exclusion Criteria: Individuals who recently underwent treatment with electroconvulsive therapy, have a history of epilepsy or other severe neurological problems, have experienced a head injury, are cognitively impaired, and have comorbid conditions such as liver, renal, cardiovascular, neurological, or endocrine, or respiratory problems, or are pregnant or nursing mothers

Locations (1)

Combined Military Hospital (CMH)

Multan, Punjab Province, Pakistan

Outcomes

Primary Outcomes

Change in severity of depressive symptoms

Change in severity of depressive symptoms, measured by the difference in mean scores on the Beck Depression Inventory-II (BDI-II) from baseline to 4 weeks post-intervention

Time frame: Four Weeks

Data from ClinicalTrials.gov

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