Changes in Scalp Condition After Using a Moisturizer: a Prospective Clinical Trial Using Artificial Intelligence

Overview

The goal of this clinical trial is to evaluate whether a scalp moisturizer containing celastrol and Cichorium intybus root extract can improve scalp condition in adults aged 19 years or older who require scalp moisturization due to dryness, scaling, erythema, or dandruff. The main questions it aims to answer are: Does once-daily application of the study moisturizer improve scalp condition from baseline to week 4, as assessed by SPI-AI (Scalp Photographic Index-Artificial Intelligence)? Does the moisturizer improve scalp biophysical parameters (erythema index, stratum corneum hydration, and transepidermal water loss) and patient-reported symptom severity over the 4-week treatment period? Participants will: Apply the study moisturizer once daily at bedtime to dry scalp for 4 weeks and rinse it off the following morning using their usual shampoo. Attend study visits at baseline (week 0), week 2, and week 4 for scalp imaging, biophysical measurements, symptom questionnaires, adherence assessment, and safety monitoring.

Conditions