This is an open-label, single-center, single-dose study.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
8
subcutaneous injection
Shandong Provincial Qianfoshan Hospital
Jinan, Shandong, China
Total radioactivity recovery and cumulative recovery in urine and feces in each time period;
To quantitatively analyze the total radioactivity in the excretions of healthy participants after subcutaneous injection of 14C-RAY1225, and to obtain the primary radioactivity recovery data and primary excretion pathways in humans;
Time frame: DAY1~DAY60
Radioactivity of each metabolite in urine and feces as a percentage of the total administered dose and the circulating metabolites in plasma as a percentage of the total exposure AUC (%AUC);
Time frame: DAY1~DAY60
Occurrence of adverse events/significant adverse events/serious adverse events
Time frame: DAY1~DAY60
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