his study aims to examine the validity and reliability of the Timed Up and Go (TUG) test in patients with Multiple Sclerosis (MS) under dual-task conditions, where participants perform both a motor and a cognitive task at the same time. MS affects movement, balance, and cognitive functions, which can lead to difficulties in walking and increased risk of falls. In this study, volunteers with MS will be asked to perform the TUG test in different conditions: Single-task TUG: walking, standing up, and sitting down without additional tasks. Cognitive dual-task TUG: performing TUG while doing a cognitive task, such as counting backwards or word generation. Motor dual-task TUG: performing TUG while carrying a small object on a tray. Participants' demographic and clinical information will be recorded, and tests will be repeated to evaluate the reliability of the measurements. The results will help determine if the TUG test can reliably assess both motor and cognitive performance in MS patients. The study is observational, and no experimental treatment will be given. Participation involves only performing tests and answering questions, taking approximately 25-30 minutes per session. All collected data will be kept confidential.
This study investigates the validity and reliability of the Timed Up and Go (TUG) test under dual-task conditions in patients with Multiple Sclerosis (MS). MS is a chronic neurological disease that affects motor and cognitive functions, often leading to walking difficulties, balance problems, and increased risk of falls. Volunteers with MS will be recruited from the Neurological Rehabilitation Unit at SANKO University. Eligible participants will perform the TUG test in three conditions: Single-task TUG: normal TUG without additional tasks. Cognitive dual-task TUG (kSKYT): performing TUG while counting backwards in threes or generating words starting with a specific letter. Motor dual-task TUG (mSKYT): performing TUG while carrying a small ball on a tray. Participants' demographic and clinical data, including age, sex, height, weight, MS duration, EDSS score, and history of falls, will be recorded. TUG tests will be conducted by two physiotherapists and repeated after one week to assess test-retest reliability and inter-rater reliability. Convergent validity will be evaluated by comparing dual-task TUG results with single-task TUG, 25-step walking test, Mini-BESTest, and a dual-task questionnaire. Known-groups validity will be assessed by comparing results between MS patients who have fallen and those who have not. All data will be coded and stored confidentially. The study is observational, with no experimental interventions, and each assessment session will take approximately 25-30 minutes.
Study Type
OBSERVATIONAL
Enrollment
50
Sanko Unıversıty
Gaziantep, Gaziantep, Turkey (Türkiye)
Sit-to-Stand and Walk Test (SKYT)
SKYT is a test that assesses an individual's functional mobility, balance, and walking performance, including sitting, standing up, walking, turning, and sitting back down. The participant is asked to walk 3 metres and
Time frame: 1 week
Dual-task SKYT tests
Dual-task SKYT tests will consist of three different dual-task SKYT tests: two cognitive dual-task SKYT tests (cSKYT) and one motor dual-task SKYT test (mSKYT). The cognitive task parameters of the cSKYT will be numerical processing
Time frame: one weeks
The 25-step walk test (S25AYT)
This is a standardised test used to assess walking speed and functional mobility in MS patients, performed by walking a distance of 7.62 metres as quickly and safely as possible. The test has been reported to have high rel
Time frame: one weeks
Dual-task questionnaire
The questionnaire was originally developed to assess individuals with neurological injury or disease and is used to evaluate the frequency of difficulties experienced in daily activities involving dual tasks. The questionnaire consists of 10 items, and each question is rated on a 5-point scale (0 = 'never' to 4 = 'very often' or N/A = 'not applicable'). The resulting score is the average score per question (questionnaire score = total questionnaire score/10). Its validity and reliability in the Turkish MS population have been demonstrated.
Time frame: one weeks
Mini-BESTest
A test frequently used in neurological disease populations that assesses the dynamic components of balance control. Participants are asked to perform various balance tasks (e.g., postural responses, sensorimotor strategies, dynamic walking). Studies conducted in MS patients have demonstrated that the Mini-BESTest has high reliability and validity in the Turkish neurological population, including MS.
Time frame: one weeks
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