This study is looking at whether Pilates-based exercise can help with hypermobility-related symptoms, like pain.
In this study, investigators are looking at whether 6 weeks of Pilates-based exercise led by a licensed physical therapist can help with hypermobility-related symptoms, like pain. Pilates is a gentle mind-body exercise with an emphasis on muscular control, postural awareness, and breathing that may be particularly well-suited for managing hypermobility. Exercises are mostly floor-based and focus on developing muscular strength and stability which may improve pain and symptom management.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
100
Pilates is a gentle mind-body exercise with an emphasis on muscular control, postural awareness, and breathing that may be particularly well-suited for managing hypermobility. Exercises are mostly floor-based and focus on developing muscular strength and stability which may improve pain and symptom management
Educational seminars pertaining to hypermobility symptom management
Brigham and Women's Hospital
Chestnut Hill, Massachusetts, United States
Intervention Feasibility
Recruitment, Retention, Attendance
Time frame: Enrollment to end of intervention (week 6) and follow-up (week 12)
Acceptability
Treatment Helpfulness Questionnaire (THQ): The THQ is a single-item measure that evaluates the perception of helpfulness of an intervention. Participants will be asked to rate the helpfulness of the intervention to which they are randomized on a scale of -5 (extremely harmful) to 5 (extremely helpful) with 0 indicating "neutral."
Time frame: Enrollment to end of intervention (week 6)
Pain intensity
The Patient Reported Outcomes Measurement Information System Profile (PROMIS-29) will be used to assess pain intensity. Scores range from 8-40 with higher scores indicating a greater presence of the corresponding construct.
Time frame: Baseline, week 6 and week 12
Pain interference
The Patient Reported Outcomes Measurement Information System Profile (PROMIS-29) will be used to assess pain interference. Scores range from 8-40 with higher scores indicating a greater presence of the corresponding construct.
Time frame: Baseline, week 6 and week 12
Bristol Questionnaire
The Bristol Impact of Hypermobility Questionnaire will be used to assess the self-reported functional impact of joint hypermobility. Higher scores indicate more severe functional impact
Time frame: Baseline, week 6 and week 12
WPI
The Widespread Pain Inventory (WPI) will be used to assess the widespreadness of body pain. Scores range from 0-19 with higher scores indicating more widespread pain.
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Time frame: Baseline, week 6 and week 12
PCS
The Pain Catastrophizing Scale (PCS) will be used to assess pain-related rumination, magnification, and helplessness in response to pain. Scores range from 0-52 with higher scores indicating more pain catastrophizing.
Time frame: Baseline, week 6 and week 12
MAIA-2
The Multidimensional Assessment of Interoceptive Awareness-2 (MAIA-2) will be used to assess 8 domains pertaining to beliefs about the body and tendencies to be internally focused, including noticing, not distracting, not worrying, attention regulation, emotional awareness, body listening and trusting. Scores range from 0-5 with higher scores indicating higher interoceptive sensibility.
Time frame: Baseline, week 6 and week 12
TSK
The Tampa Scale of Kinesiophobia (TSK) will be used to assess fear of movement. Scores range from 17-68 with higher scores indicating more fear of movement.
Time frame: Baseline, week 6 and week 12
SHS
The Sensory Hypersensitivity Scale (SHS) will be used to assess multisensory sensitivity to items related to sensitivity to light, heat, cold, allergies, pain, smell, hearing, taste, and touch. Higher scores indicate more multisensory sensitivity. The scale will be modified to include an additional rating of bothersomeness from 1 (Not bothersome at all) to 5 (Extremely bothersome) for each of the original scale items to evaluate multisensory bothersomeness
Time frame: Baseline, week 6 and week 12
Overall physical and mental health
The Patient Reported Outcomes Measurement Information System Profile (PROMIS-29) will be used to assess overall physical and mental health, with subscales including physical function, anxiety, depression, fatigue, social participation, and sleep disturbance. Scores range from 8-40 with higher scores indicating a greater degree of the corresponding construct
Time frame: Baseline, week 6 and week 12
Heartrate Variability
resting HRV
Time frame: Enrollment to end of intervention (week 6) and follow-up (week 12)
Functional mobility
Functional mobility will be assessed using the Timed Up and Go (TUG) test
Time frame: Enrollment to end of intervention (week 6) and follow-up (week 12)
Functional endurance
Functional endurance will be measured with the 2-minute walk test (2MWT)
Time frame: Enrollment to end of intervention (week 6) and follow-up (week 12)