Cohort Study of Chronic Liver Disease Complicated by Sepsis

N/ANot Yet RecruitingNCT07465003

The Second Affiliated Hospital of Chongqing Medical University1,600 enrolled

Overview

Study population: Patients with liver cirrhosis complicated by sepsis Observation indicators: Fluid resuscitation strategy, early dynamic indicators such as MAP Observation endpoint: 28-day all-cause mortality Study design: Retrospective cohort study

Study Type

OBSERVATIONAL

Enrollment

1,600

Conditions

Cirrhosis Sepsis

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Clinically or pathologically diagnosed with cirrhosis; * meets the Sepsis-3 diagnostic criteria. Exclusion Criteria: * Combined organ transplantation, active malignant tumors; * Pregnant or breastfeeding women; * Long-term use of immunosuppressants (non-steroidal); * Death or voluntary discharge within 24 hours of admission; * Incomplete data.

Outcomes

Primary Outcomes

28-day all-cause mortality in cirrhosis with sepsis

Time frame: Baseline and 28 days.

Central Contacts

Li ShiYing Deputy Chief Physician of the Department of Infectious Disease, Ph.D

CONTACT

0086+18623322462 302946@hospital.cqmu.edu.cn

Data from ClinicalTrials.gov

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