The purpose of this trial is to assess relative bioavailability of centanafadine (CTN) SR tablet to CTN QD XR capsule in healthy adult participants.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
62
Oral tablets.
Oral capsules.
ICON, plc.,
Lenexa, Kansas, United States
Area Under the Concentration-time Curve Calculated to the Last Observable Concentration at Time t (AUCt) of Centanafadine
Time frame: Up to Day 6
Area Under the Concentration-time Curve From Time Zero to Infinity (AUCinfinity) of Centanafadine
Time frame: Up to Day 6
Maximum Plasma Concentration (Cmax) of Centanafadine
Time frame: Up to Day 6
Time to Maximum Plasma Concentration (Tmax) of Centanafadine
Time frame: Up to Day 6
Terminal-phase Eimination Half-life (T1/2z) of Centanafadine
Time frame: Up to Day 6
Apparent Clearance of Drug From Plasma After Extravascular Administration (CL/F) of Centanafadine
Time frame: Up to Day 6
AUCt of Centanafadine Under Fasted and Fed Conditions
Time frame: Up to Day 6
AUCinfinity of Centanafadine Under Fasted and Fed Conditions
Time frame: Up to Day 6
Cmax of Centanafadine Under Fasted and Fed Conditions
Time frame: Up to Day 6
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