High-Frequency rTMS Over the DLPFC for Chronic Low Back Pain

Overview

Neuropathic pain is a chronic condition that significantly affects quality of life and often responds poorly to conventional pharmacological treatments. Repetitive transcranial magnetic stimulation (rTMS) has emerged as a non-invasive neuromodulation technique with potential analgesic effects. This study aimed to evaluate the effectiveness of rTMS in reducing neuropathic pain intensity among patients with confirmed neuropathic pain. A clinical study was conducted involving adult patients who met diagnostic criteria for neuropathic pain. Participants received rTMS sessions targeting the motor cortex over a defined treatment period. Pain intensity was assessed using standardized pain scales before and after treatment. The study examined changes in pain scores following rTMS therapy and evaluated its potential as an adjunctive treatment for neuropathic pain. The findings of this study may contribute to understanding the therapeutic role of rTMS in the management of neuropathic pain and support its use as a non-invasive treatment option.

Neuropathic pain is caused by lesions or diseases affecting the somatosensory nervous system and is often difficult to manage with conventional pharmacological treatments. Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive neuromodulation technique that modulates cortical excitability and has been investigated as a potential treatment for neuropathic pain. This study was conducted to evaluate the effectiveness of rTMS therapy in patients diagnosed with neuropathic pain. Eligible patients who met the diagnostic criteria for neuropathic pain were enrolled and received rTMS stimulation targeting the primary motor cortex (M1). The stimulation protocol followed standard clinical parameters used for pain modulation. Participants underwent multiple rTMS sessions during the treatment period. Pain intensity was evaluated using validated pain assessment scales before treatment and after completion of the rTMS sessions. The primary objective was to determine whether rTMS therapy could significantly reduce pain intensity in patients with neuropathic pain. Secondary observations included the tolerability of the intervention and clinical responses among participants following the stimulation protocol. Data were analyzed to compare pain scores before and after treatment. The study was conducted in accordance with ethical standards and approved by the institutional ethics committee. The results aim to provide evidence regarding the role of rTMS as a therapeutic option for neuropathic pain management.