Development of a Non-Invasive Prognostic Test for Graves Orbitopathy

N/AActive Not RecruitingNCT07472062

University Hospital, Ghent90 enrolled

Overview

The aim of this research project is to develop a non-invasive, simple, robust, and sensitive prognostic test that can identify hyperthyroidism patients who are at risk of developing Graves' Orbitopathy. This phase of the study is a research phase in which we analyze blood samples and tear fluid using standard laboratory equipment and software. The aim is to identify biomarkers that can detect patients at risk of developing Graves' Orbitopathy. Offering more personalized advice, treatment, and follow-up could potentially prevent the clinical consequences or limit their severity.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

SUPPORTIVE_CARE

Masking

NONE

Enrollment

Conditions

Graves Orbitopathy Hyperthyroidism

Interventions

Collection of tears with Schirmer's test

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy control OR diagnosis of hyperthyroidism OR diagnosis of Graves' Orbitopathy Exclusion Criteria: * \<18 y/o

Locations (1)

Ghent University Hospital

Ghent, Belgium

Outcomes

Primary Outcomes

Biomarkers found in tears collected at Baseline

During a one-day study visit (Baseline visit), tears will be collected from all study participants via a Schirmer's test.

Time frame: Baseline

Data from ClinicalTrials.gov

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