Early Coronary Angiography in Advanced Chronic Kidney Disease With Acute Coronary Syndrome

Chulalongkorn University139 enrolled

Overview

This is the retrospective study regarding the association of invasive coronary angiography and time to renal replacement therapy initiation and mortality in patients with chronic kidney disease stage 4-5 who develop acute coronary syndrome.

Electronic medical records of adult patients admitted with ACS, by the recorded diagnosis code, between 1 January 2017 and 31 December 2021 at King Chulalongkorn Memorial Hospital, Thailand, were retrospectively reviewed. Eligible patients should have concurrent advanced stage CKD, defined as an eGFR less than 30 mL/min/1.73 m² calculated by the 2021 CKD-EPI creatinine equation.

Study Type

OBSERVATIONAL

Enrollment

139

Conditions

CKD ACS (Acute Coronary Syndrome)Coronary Angiography (CAG)

Interventions

coronary angiographyPROCEDURE

Standard coronary angiography

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Advanced stage CKD, defined as an eGFR less than 30 mL/min/1.73 m² * Diagnosis with ACS, by the recorded diagnosis code, between 1 January 2017 and 31 December 2021 at King Chulalongkorn Memorial Hospital Exclusion Criteria: * Received maintenance dialysis or kidney transplantation before admission * Cardiogenic shock or cardiac arrest * Prior PCI or CABG within 12 months * Recently diagnosed with ACS within 2 months * Had a limited life expectancy due to non-cardiovascular disease * Pregnant.

Outcomes

Primary Outcomes

Renal replacement therapy initiation

Time frame: Until 31 December 2021

Secondary Outcomes

All-cause mortality

Time frame: Until 31 Dec 2021

Data from ClinicalTrials.gov

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