Lung cancer remains a leading cause of morbidity and mortality, and resective surgery is the treatment of choice in operable stages. However, a significant proportion of patients present with functional impairment prior to surgery and develop postoperative complications, especially respiratory ones. Prehabilitation has become established as a strategy capable of optimizing physical condition before surgery, while early rehabilitation contributes to accelerating recovery after discharge. Nevertheless, its routine implementation is limited by logistical barriers, short waiting times, and difficulties in accessing in-person care. The PulmoSalud project proposes a multimodal program, consisting of 8 weeks of prehabilitation (strength and endurance exercises, and respiratory physiotherapy) and 4 weeks of early home-based rehabilitation, supported by a specific digital application, in order to facilitate continuity of care without the need for additional travel. The content includes progressive strength training, structured breathing exercises (including inspiratory muscle training), educational guidelines, and digital recording of activity and symptoms. Patients will receive initial in-person training to ensure the correct execution of the exercises, and will subsequently continue independently with remote supervision. A controlled study will be conducted comparing this program with the center's standard care. Functional variables (aerobic capacity, muscle strength), respiratory parameters, postoperative complications, quality of life, self-efficacy, and healthcare resource utilization will be evaluated. Measurements will be taken at three time points: baseline (T0), immediate pre-surgical (T1), and one month post-surgery (T2). PulmoSalud aims to improve preoperative preparation, accelerate post-surgical recovery, and reduce the burden on healthcare services by safely integrating a home-based intervention supported by digital technology.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
84
1. Warm-up and mobility (8-10 minutes): Overall mobility of the spine, shoulder girdle, and hips; light walking or cycling; progressive muscle activation. 2. Aerobic training (12-20 minutes): Options include walking, treadmill, or stationary cycling. Moderate intervals (light HIIT). 3. Strength training (15-25 minutes): Performed with resistance bands, light dumbbells, and bodyweight exercises, with special emphasis on the lower limbs and relevant scapular muscles following thoracic surgery: assisted squats or sit-to-stand exercises; low and high banded rows; chest presses with bands or light dumbbells; hip raises; lateral marches with bands; scapular work (retraction, Y-T-W). 4. Cool-down (5-8 minutes): Thoracic and scapular mobility exercises; controlled breathing (coordinated with respiratory physiotherapy). Independent home session (1 time/week): Performed with the support of the PulmoSalud application.
1. Initial recovery: Light walking 10-15 min/day, RPE 2-3, very basic strength exercises (1 set): Supported sit-to-stand, lateral walking, gentle scapular retraction, strengthening of thoracic mobility, and breathing exercises from the clinical protocol. 2. Progressive functional recovery: Walking 15-25 min/day, RPE 4-5, introduction of light intervals (30 seconds fast / 90 seconds slow), strength circuit (2 sets): Assisted squat, banded row, hip thrust, add scapular work as tolerated.
Re-education and control of the respiratory pattern, Lung expansion exercises (EDIC) and segmental ventilation, Basic secretion management techniques, Scar protection education and cough management (videos + daily practice), Thoracic mobility and gentle non-impact physical activity, Inspiratory muscle training (IMT), Mobile application (App) for support during postoperative rehabilitation.
The app will be used as an educational tool and for self-monitoring by the patient, allowing them to record basic parameters daily, such as dyspnea (Borg scale), pain, sleep quality, and adherence to exercise sessions, IMT (Inspiratory Muscle Training), and breathing exercises. The app includes demonstration videos of breathing techniques, education on scar protection, and preoperative preparation materials, as well as scheduled notifications for IMT, chest expansion exercises, and physical activity, in addition to brief self-assessment quizzes. The app's use will be exclusively educational and to support self-management, without remote monitoring or transmission of clinical data to the healthcare team.
Re-education and control of the breathing pattern, Lung expansion exercises and directed ventilation, Safe bronchial hygiene techniques, Scar protective education and effective pain-free coughing strategies, Inspiratory muscle training, Whole body ventilatory training.
6 minute walk test (6MWT): continuous quantitative variable (meters).
Time frame: From the start of treatment until its completion at 12 weeks
30-Second Sit-to-Stand Test
Time frame: From the start of treatment until its completion at 12 weeks
FEV1 (L and % predicted)
Time frame: From the start of treatment until its completion at 12 weeks.
FVC (L and % predicted)
Time frame: From the start of treatment until its completion at 12 weeks.
FEV1/FVC:
Time frame: From the start of treatment until its completion at 12 weeks.
maximum inspiratory pressure (MIP) and maximum expiratory pressure (MEP)
Time frame: From the start of treatment until its completion at 12 weeks.
Peak Cough Flow (PCF)
Time frame: From the start of treatment until its completion at 12 weeks.
mMRC scale
Time frame: From the start of treatment until its completion at 12 weeks.
modified Borg scale
Time frame: From the start of treatment until its completion at 12 weeks.
Hand grip dynamometry
Time frame: From the start of treatment until its completion at 12 weeks.
Estimated maximum strength 1RM
Time frame: From the start of treatment until its completion at 12 weeks
Bruce's ramp test
Time frame: From the start of treatment until its completion at 12 weeks
Submaximal heart rate reached (80%, heart rate monitor)
Time frame: From the start of treatment until its completion at 12 weeks
FAACT-A/CS Questionnaire (anorexia-cachexia)
Time frame: From the start of treatment until its completion at 12 weeks
diet quality
Time frame: From the start of treatment until its completion at 12 weeks
International Physical Activity Questionnaire (IPAQ)
Time frame: From the start of treatment until its completion at 12 weeks
Godin questionnaire
Time frame: From the start of treatment until its completion at 12 weeks
Subjective perception of effort (RPE, scale 0-10)
Time frame: From the start of treatment until its completion at 12 weeks
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