Effects of Transversus Abdominis Plane Block on Recovery Quality and Maternal-Neonatal Outcomes After Cesarean Delivery

Qing Yuan83 enrolled

Overview

ltrasound-guided transversus abdominis plane (TAP) block is an emerging local anesthesia technique that effectively alleviates postoperative pain by injecting anesthetic drugs around the nerves in the abdominal wall. Compared with traditional analgesic methods, TAP blockade may have better analgesic effects and fewer side effects. However, current research on the application of TAP blockade after cesarean section is still limited. Therefore, this study will systematically evaluate its actual effectiveness in pain management after cesarean section through a prospective randomized controlled trial

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

PREVENTION

Masking

DOUBLE

Enrollment

Conditions

Postoperative Pain After Cesarean Section

Interventions

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Aged 20-40 years, in good general health * ASA physical status I-II * Singleton, term (37-41 weeks) pregnancy with normal fetal development * Planned for elective cesarean section, no labor Exclusion Criteria: * Pregnancy complications (e.g., severe preeclampsia, gestational diabetes, placental abruption) * Major organ dysfunction (heart, liver, kidney) or psychiatric history * Allergy to local anesthetics or any study drugs * Prior abdominal surgery or infection that may affect block efficacy * Coagulation disorders or current anticoagulant use * Refusal to participate or inability to comply with follow-up

Locations (2)

Shandong Provincial Maternal and Child Health Care Hospital

Jinan, Shandong, China

Shandong Provincial Maternal and Child Health Care Hospital

Jinan, Shandong, China

Outcomes

Primary Outcomes

VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity ( Time to first rescue analgesia requirement and number of patients and total dosage of flurbiprofen axetil used within 48 hours postoperatively;

VAS pain scores (0-10 scale, where 0 = no pain and 10 = unbearable severe pain) at rest and during activity (coughing or turning) at 2, 6, 12, 24, and 48 hours postoperatively were recorded by anesthesiologists not involved in this study.

Time frame: 5 months