This study aims to assess the value of endosonographic patterns of EBUS bronchoscopy in diagnosis of patients with mediastinal lymphadenopathy and correlate it with the histopathological diagnosis.
All patients will undergo EBUS-bronchoscopy using 22-gauge needle of EBUS. * Lymph node stations and numbers were determined according to the International Association for the Study of Lung Cancer classification. * Systemic evaluation of Lymph nodes according to ERS guidelines starting with any potential N3 lymph nodes followed by N2 lymph nodes, and N1 lymph nodes Ultrasound features of suspected lymph nodes were categorized according to: B-mode, Color Power Doppler Index (CPDI) After evaluation of ultrasound features, a TBNA using a 22- G needle were performed. Three samples were taken from each node or lesion for +/- rapid on-site evaluation ROSE (using Haematoxylin and Eosin stain) and histopathological examination.
Study Type
OBSERVATIONAL
Enrollment
50
Ain Shams University
Cairo, Abbassia, Egypt
1- evaluate the morphological characteristics of mediastinal LNs in real time 2- assess the nature of LNs before puncturing either benign or malignant using EBUS and corelate them with the histopathological outcome.
1. EBUS sonographic features can guide the selection of LNs for biopsy 2. EBUS sonographic features can guide internal puncture site within the LN and biopsy efficiency as a complementary diagnostic value.
Time frame: 2 years
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