LFP-based Parameter Prediction in DBS for Parkinson's Disease

Loes Laurijssen40 enrolled

Overview

The goal of this observational study is to assess whether deep brain stimulation (DBS) contact selection in Parkinson's disease could be informed by subcortical local field potential (LFP) recordings. The main question it aims to answer is: Aligns stimulation contact selection based on subcortical LFP recordings with clinically optimized contact selection? Participants will undergo LFP recordings that are part of standard clinical care during their routine hospital visits.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Parkinson's Disease (PD)

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. Voluntary written informed consent of the participant 2. At least 18 years of age at the time of signing the Informed Consent Form (ICF) 3. Diagnosis of idiopathic Parkinson's disease according to the clinical diagnostic criteria of the Movement Disorder Society (MDS) 4. Eligible for DBS to treat refractory PD motor symptoms, as based on multidisciplinary DBS screening 5. Have sufficient understanding of the Dutch and French language to participate in the study Exclusion Criteria: * /

Locations (1)

University Hospitals Leuven

Leuven, Vlaams-Brabant, Belgium

RECRUITING

Outcomes

Primary Outcomes

Alignment of contact selection

Alignment between local field potential-based contact selection and the clinically optimized stimulation contact.

Time frame: From the first LFP recording to the last LFP recording (6 - 9 months)

Central Contacts

Bart Swinnen, MD, PhD

CONTACT

0032 16343044 bart.swinnen@uzleuven.be

Data from ClinicalTrials.gov

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