To conduct a multi-center, randomized, controlled clinical study aimed at formally evaluating the impact of pressing therapy on the success rate in patients with recurrent implantation failure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
208
nonpenetrating placebo needles
indwelling intradermal needles
Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology
Wuhan, Hubei, China
clinical pregnancy
defined as ultrasonographic detection of an intrauterine gestational sac following embryo transfer
Time frame: 1 year
β-hCG-positive pregnancy
defined as serum β-hCG concentration \>10 mIU/mL on day 14 post-transfer
Time frame: 1 year
Endometrial thickness
Endometrial thickness on Transformation Day
Time frame: 1 year
endometrial blood flow
Time frame: 1 year
anxiety assessment
Time frame: 1 year
depression assessment
Time frame: 1 year
sleep quality assessment
Time frame: 1 year
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