The goal of this clinical trial is to learn whether giving less intravenous (IV) fluid (restrictive administration) after surgery is as effective as giving more IV fluid (liberal administration) in maintaining body stability (homeostasis) among adults undergoing laparoscopic gallbladder removal (cholecystectomy). The main questions it aims to answer are: Does restrictive IV fluid administration maintain stable blood pressure, heart rate, and urine output after laparoscopic cholecystectomy? Are there any differences in postoperative recovery or complications between restrictive and liberal fluid regimens? Researchers will compare patients receiving liberal IV fluid administration with those receiving restrictive IV fluid administration to see if both methods maintain similar postoperative homeostasis and recovery outcomes. Participants will: Be adults aged 18-60 years (ASA class I-II) undergoing elective laparoscopic cholecystectomy. Be randomly assigned to one of two groups: Group A: Liberal IV fluid administration for 6 hours after surgery. Group B: Restrictive IV fluid administration for 6 hours after surgery. Have their vital signs (pulse, blood pressure, mean arterial pressure) and urine output recorded at multiple time points after surgery (immediate, 3, 6, 12, and 24 hours).
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
380
500ml ringer lactate perioperatively given in laparoscopic cholecystectomy patients as compared to traditional 1000ml fluid
1000ml iv fluid given perioperatively in laparoscopic cholecystectomy
King Edward Medical University Lahore / Mayo Hospital Lahore
Lahore, Punjab Province, Pakistan
RECRUITINGMean Systolic Blood Pressure
Mean systolic blood pressure at preoperative and 3,6, 12 and 24 hours post operatively
Time frame: Day 1
Mean Pulse Rate Per Minute
Mean pulse rate per minute at pre operative, 3,6,12 and 24 hours post operatively
Time frame: Day 1
Mean Diastolic Blood Pressure
Mean diastolic blood pressure at pre operative, 3,6,12 and 24 hours post operatively
Time frame: Day 1
Mean Pulse Pressure
Mean pulse pressure at pre operative, 3,6,12 and 24 hours post operatively
Time frame: Day 1
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