Mesh Infection After Hernioplasty: Complete vs Partial Removal - Retrospective Study on Outcomes and Pathogen Analysis

N/ANot Yet RecruitingNCT07491250

Fudan University100 enrolled

Overview

Background: Mesh infection after tension-free inguinal hernia repair (IHR) is rare and challenging. When conservative treatment fails, surgery is often required. This study compared clinical outcomes of complete versus partial mesh removal in affected patients. Materials and Methods: We retrospectively analyzed patients who underwent surgery for mesh infection after IHR in our hospital between January 2016 and December 2025. Baseline data, perioperative indicators, postoperative complications, and microbiological results were compared between the complete and partial removal groups.

We conducted a single-center, retrospective case series analysis. We included patients who developed mesh infection after tension-free IHR and underwent surgical treatment at our center between January 2016 and December 2025. Patients with mesh infection after incisional, parastomal, or umbilical hernia repair were excluded. We also excluded patients who improved with conservative treatment and did not undergo surgery. We collected the following data: demographic characteristics, comorbidities, laboratory and imaging results, characteristics of the primary hernia surgery, infection characteristics, intraoperative data, and postoperative outcomes. All data were entered into a standardized database. Follow-up was conducted through outpatient visits and telephone interviews. The last follow-up was on October 30, 2025.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Inguinal Hernia Repair Mesh Infection

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Patients who underwent tension-free inguinal hernioplasty with mesh placement. 2. Patients diagnosed with mesh infection requiring surgical re-intervention. 3. Patients who underwent complete or partial mesh removal surgery. 4. Availability of complete medical records and follow-up data. Exclusion Criteria: 1. Patients with mesh infection managed conservatively (without surgical removal). 2. Patients with missing critical data (e.g., intraoperative findings, pathogen results, or follow-up). 3. Patients with concomitant procedures that could confound outcomes (e.g., simultaneous other hernia repair). 4. Patients lost to follow-up immediately after discharge (no postoperative assessment).

Outcomes

Primary Outcomes

Hernia Recurrence Rate

Presence of clinically or radiologically confirmed recurrent inguinal hernia at the site of previous hernioplasty following mesh removal surgery.

Time frame: From date of surgery to December 2025

Infection Recurrence Rate

Recurrence of surgical site infection at the same location after initial surgical treatment for mesh infection, confirmed by clinical signs (e.g., erythema, purulent drainage, sinus tract formation) and/or positive microbiological culture.