Comparison of Efficacy of Topical Westerhoff Formula Cream Vs Topical 4% Hydroquinone for the Treatment of Melasma

Phase 4CompletedNCT07508098

Pak Emirates Military Hospital50 enrolled

Overview

study was conducted on middle aged male and female, including families and health care professional also.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Melasma (Facial Melasma)

Interventions

Triple combination creamDRUG

4.7% N-acetylcysteine, 2% Hydroquinone and 0.1 % triamcinolone acetate twice daily for 8 weeks

Hydroquinone 4% CreamDRUG

twice daily for 8 weeks

Eligibility

Sex: ALLMin age: 15 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patient with facial melasma of age between 15 years to 45 years of both gender Exclusion Criteria: * patient who have already taken treatment within 8 weeks, pregnant women, who are taking hormonals therapy and patient of dementia

Locations (1)

Dermatology Department of Tertiary Care Hospital

Rawalpindi, Punjab Province, Pakistan

Outcomes

Primary Outcomes

proportion of participants achieving 60% reduction in the melasma area severity index (MASI-60)

the primary outcome is the proportion of the participants achieving 60% reduction in MASI score from baseline after 8 weeks of treatment. MASI is the scoring system used to assess the melasma on the basis of severity darkness and the homogeneityenicity

Time frame: 8 weeks

proportion of participants achieving >60% reduction in Melasma Area and severity index (MASI-60)

The primary outcome is the proportion of the participants achieving 60% reduction in MASI Score rom the baseline after treatment. MASI is the scoring system used to assess the severity of melasma based on the area, darkness nd the homogeneity

Time frame: baseline to 8 weeks

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.