The purpose of this study is to evaluate the therapeutic efficacy of transcutaneous electrical acupoint stimulation for cisplatin- chemotherapy induced nausea and vomiting.
Chemotherapy-induced nausea and vomiting significantly impacts the quality of life for 70%-80% of cancer patients receiving chemotherapy. The P6 acupressure point is traditionally used to relieve these symptoms and has shown benefits in pain relief and other conditions. If studies on Transcutaneous electrical acupoint stimulation yield positive results, it could be integrated as an effective method to manage chemotherapy-induced nausea and vomiting, enhancing patient comfort and treatment outcomes while potentially reducing the need for dosage adjustments. This study aims to address gaps in current treatments, improving management and quality of life for affected cancer patients.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
34
The acupoints were wiped with a moist cotton swab and then connected to the anode and cathode of the electrical stimulation generator through an electrode patch placed on the skin surface. Continuous wave form mode was selected, and then the electric current produced continuous stimulation on the acupoints. Stimulation frequency was set at 4 Hz, and the default value was set as 10 mA, which was twice the sensory threshold (5 mA). The intensity was adjusted every 10 min to keep the patients comfortable, and its actual value ranged from 7 to 15 mA.
the drug is being taken once a day for 72 hours after introducing chemotherapy
National Cancer Institute in Damietta.
Damietta, Egypt
Assessment of nausea
The M. D. Anderson Symptom Inventory MD Anderson Symptom Inventory is a multi-symptom patient-reported outcome measure for clinical and research use. The MD Anderson Symptom Inventory 's thirteen core items include symptoms found to have the highest frequency and/or severity in patients with various cancers and treatment types. Each symptom is being scored between 0 and 10, were 0 means no effect and 10 means greatest severity.
Time frame: At the day of chemotherapy administration and the following 5 days
Assessment of vomiting
Visual analog scale for anorexia is a widely used tool for assessing subjective symptoms, including anorexia. It consists of a horizontal or vertical line, typically 100 mm long, where patients mark their perceived intensity of a symptom-ranging from "no anorexia" to "worst possible anorexia"
Time frame: At the day of chemotherapy administration and the following 5 days
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