Optimal Allogeneic PRP Concentration for Oocyte In Vitro Maturation in Women With PCOS

Inclusion Criteria: * Immature oocytes at the germinal vesicle (GV) stage * Oocytes obtained from patients fulfilling clinical and laboratory diagnostic criteria for PCOS, defined by the presence of at least two of the following three characteristics: clinical hyperandrogenism and/or biochemical hyperandrogenemia, ovulatory dysfunction (oligomenorrhea or anovulation), and polycystic ovarian morphology (≥12 follicles measuring 2-9 mm in each ovary on ultrasonography) * Oocytes collected from patients undergoing ovarian stimulation using the same ovarian stimulation protocol. * Oocytes obtained from patients with primary infertility * Oocytes obtained from treatment-naive patients with PCOS. Exclusion Criteria: \- Oocytes obtained from patients with comorbid conditions, including cancer, congenital adrenal hyperplasia, Cushing's syndrome, premature ovarian failure (POF) or premature ovarian insufficiency, liver disorders, kidney disease, cardiovascular disease, diabetes mellitus (type 1 or type 2), and patients receiving steroid therapy