biological assesment during intrusion of lower incisors
Assessment of the biological response of the corticision during intrusion of lower incisors A prospective clinical study
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
NONE
Enrollment
16
1. Prior panoramic x-ray or serial periapical x-rays are essential to assure the availability of interradicular room to carry out the procedure. 2. Preoperative antiseptic mouthwash is administered to prevent potential infections. 3. Infiltration anesthesia is applied. 4. A reinforced 15T scalpel is positioned on the interradicular attached gingiva at an inclination of 45-60 degrees on the long axis of the tooth to be moved.
Gingival crevicular fluid (GCF) prostaglandin E2 (PGE2) levels measured by enzyme-linked immunosorbent assay (ELISA) (pg/mL)
GCF samples will be collected from lower incisors using microcapillary tubes at baseline and during follow-up visits. Prostaglandin E2 levels will be quantified using ELISA kits and expressed in pg/mL to assess the biological response to corticision-assisted intrusion.
Time frame: 12 weeks
Amount of lower incisor intrusion measured in millimeters (mm) using cone beam computed tomography (CBCT)
CBCT imaging will be used to measure the vertical displacement of lower incisors in millimeters by comparing pre- and post-treatment positions.
Time frame: 12 weeks
External apical root resorption measured in millimeters (mm) using cone beam computed tomography (CBCT)
CBCT imaging will be used to assess external apical root resorption by comparing root lengths before and after treatment.
Time frame: Time Frame: 12 weeks
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