Comparison of Intravitreal Anti-VEGF Treatment Burden in Different Retinal Diseases

Hospital Hietzing393 enrolled

Overview

The study compares the perceived treatment burden in patients undergoing intravitreal anti-VEGF treatment for either wet age related macular degeneration, macular edema after retinal vein occlusions or diabetic macular edema. This study is the first to the investigator's knowledge to compare treatment burden between all three patient groups, which also differ in age and socioeconomic circumstances. The results are of interest to all ophthalmologists who prescribe anti-VEGF treatments, as they show factors which can influence patient adherence und thus the efficacy of said therapies.

Study Type

OBSERVATIONAL

Enrollment

393

Conditions

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * undergone a minimum of 5 IVT's and had visited the retina clinic for at least 6 months Exclusion Criteria: * eye surgery in the preceding six months * notable cognitive impairment, such as dementia * age \<18 years

Locations (1)

Outcomes

Primary Outcomes

Severitiy of subjective treatment burden due to intravitreal anti-VEGF therapy assessed by questionnaire

The questionnaire was designed on the basis of the Longitudinal assessment of Adherence Factors to Intravitreal (anti-VEGF) Therapy (LAF-IVT) questionnaire. Patients were interviewed about their perceived treatment burden, their socioeconomic status, and demographic details. Different aspects of treatment burden were graden by the patients as "no", "little", "moderate", "great" or "extreme buden".

Time frame: From May 2023 to April 2024