To be effective, organized colorectal cancer screening requires good adherence to diagnostic colonoscopy in the event of a positive test. In France, the rate of diagnostic colonoscopy following a positive colorectal cancer screening test is less than 85%, and the median delay is close to 90 days. After receiving their positive result from the laboratory, individuals with no known follow-up are contacted only six months later by the Regional Cancer Screening Coordination Centers (CRCDC) responsible for following up with individuals who have tested positive. To optimize follow-up with colonoscopy, earlier contact and information about colonoscopy appear to be necessary. The contribution of the general practitioner identified on the test could be an additional lever. The SUIVICOLO study aims to evaluate the effectiveness on the rate of colonoscopies performed at 6 months of two strategies for optimizing the follow-up of positive results in comparison with control group C (current procedures of the CRCDC Centre Val de Loire without early letter). The two strategies evaluated will be: * Group B1: Sending an early letter signed by the CRCDC accompanied by information leaflet about colonoscopy * Group B2: Sending an early letter co-signed by the CRCDC and the general practitioner (identified or provided by the patient on the test identification form) accompanied by information leaflet about colonoscopy. These strategies will be compared to the current follow-up strategy in a three arm randomized controlled arm.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Enrollment
2,000
1. 6 months after positive test result: 1st reminder letter from the CRCDC if it has no information about a colonoscopy being performed 2. 12 months after positive test result: 2nd reminder letter from the CRCDC if it has no information about a colonoscopy being performed 3. 18 months after positive test result: 3rd reminder letter from the CRCDC if it has no information about a colonoscopy being performed
An information leaflet about colonoscopy follow-up will be sent in an early letter 7 days after positive test result, and though QR-codes in subsequent reminders.
Explicit mention of their general practitioner in letters and reminders sent by the CRCDC to individuals who have tested positive for colorectal cancer, including the information leaflet about colonoscopy or a link to this document (QR code).
Crcdc-Cvl
Tours, France, France
RECRUITINGColonoscopy rate at 6 months after a positive test
Time frame: 6 months
Percentage of general practitioners who agreed to participate in the project
Time frame: At baseline
Colonoscopy rates at 12 months after a positive test
Time frame: 12 months
Colonoscopy rates at 18 months after a positive test
Time frame: 18 months
Colonoscopy rates at 24 months after a positive test
Time frame: 24 months
Number of reminders in each group by type of reminder
Time frame: 24 months
Number of people with contraindications to colonoscopy
Time frame: 24 months
Number of people with a CT colonography
Time frame: 24 months
Time to perform colonoscopy
Time frame: 24 months
Colorectal cancer at colonoscopy
Time frame: 24 months
Advanced neoplasia at colonoscopy
Time frame: 24 months
Number of people who refused colonoscopy
Time frame: 24 months
Number of lost to follow-up
Time frame: 24 months
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