This study investigates the level and distribution of suicide risk and learned suicide ability of patients with mood disorders, investigates the related risk factors of suicide and suicide ability formation of patients with mood disorders from multiple dimensions (biological, psychological, social and clinical perspectives) and clarifies their importance, forms a list of suicide risk factors, and establishes a prediction model of learned suicide ability formation. Upon enrollment, participants will undergo comprehensive assessments including blood and urine sample collection and scale evaluation. The collection of scientific blood and urine is mainly used for the exploration of molecular mechanism of disease occurrence and development, the discovery and verification of biomarkers. Scale evaluation includes: Beck Scale for Suicide Ideation , Columbia Suicide Severity Rating Scale,, Hamilton Depression Rating Scale , Hamilton Anxiety Rating Scale, PHQ-9, GAD-7, Personal and Social Function Scale , Schihan Disability Scale , Emotional Adjustment Difficulty Scale , Acquired Capability for Suicide Scale, Interpersonal Needs Questionnaire , Ottawa Self-Injury Scale, Chinese version of Stress Perception Scale and Beck Hopelessness Scale . Follow-up was carried out for 3 months, including whether suicide/self-injury occurred, current status, and some baseline questionnaires (such as BSI-CV, GAD-7, PHQ-9, HAMD-17,HAMA, etc.).
Study Type
OBSERVATIONAL
Enrollment
300
Tianjin Anding Hospital
Tianjin, Tianjin Municipality, China
RECRUITINGColumbia Suicide Severity Rating Scale
Columbia Suicide Severity Rating Scale (C-SSRS) is a tool for evaluating the risk of individual suicide. It includes a series of questions to evaluate the frequency, intensity, persistence and concreteness of individual suicide behavior in the past period of time. Developed by researchers from Columbia University, the scale should be widely used in clinical and research fields to help identify and manage suicide risks.
Time frame: baseline, 3 months
Beck Scale for Suicide Ideation
Beck Scale for Suicide Ideation (BSI-CV): Pass. A series of questions to assess the individual's thoughts about life and death and the severity of suicidal thoughts. There are 19 items in the scale, which are divided into two dimensions: suicidal ideation and suicidal tendency. Each question is asked for two time periods, that is, the last week and the most depressed, melancholy or suicidal time in the past (that is, the most serious time). The scale adopts a three-level scoring system, that is, 0\~2 points, and the total score is between 0\~38 points. The higher the score, the stronger the suicidal ideation and the higher the risk of suicide.
Time frame: baseline, 3 months
Hamilton Depression Rating Scale
Hamilton Depression Rating Scale (HAMD-17), also known as Hamilton Depression Rating Scale, is a clinical tool for evaluating the severity of depressive symptoms, mainly evaluating patients' depressive symptoms in the past week, including mood, sleep, cognitive function, behavior and physical symptoms. According to the specific performance of patients, doctors or clinical evaluators will give corresponding scores. The higher the total score, the more serious the depressive symptoms are.
Time frame: baseline, 3 months
Hamilton Anxiety Rating Scale
Hamilton Anxiety Rating Scale (HAMA) is a clinical tool for evaluating the severity of anxiety symptoms. The scale was compiled by psychologist Hamilton in 1959, and it is widely used in clinical diagnosis, treatment effect evaluation and research work in psychiatry. HAMA contains 14 items, covering psychological anxiety and physical anxiety. Each item is scored according to the severity of symptoms, and the higher the total score, the more serious the anxiety symptoms are. Scoring standards are usually divided into four grades: mild, moderate, severe and extremely severe.
Time frame: baseline, 3 months
Patient Health Questionnare
Patient Health Question Nare (PHQ-9): It contains 9 questions, mainly focusing on depressed mood, lack of pleasure, sleep disorder, decreased energy, change of appetite, difficulty in concentration, reduced sense of self-worth, negative ideas or suicidal thoughts.
Time frame: baseline, 3 months
Generalized Anxiety Disorder
Self-rating anxiety scale, a total of 7 items, respectively: 1 nervous anxiety, 2 uncontrollable worries, 3 excessive worries, 4 inability to relax, 5 akathisia, 6 irritability, 7 sense of foreboding.
Time frame: baseline, 3 months
acquired capability for suicide scale
The scale includes two sub-scales: reduced fear of death and improved physical pain tolerance, with a total of 20 topics. Each topic is scored on a 5-point Lickert scale of 1 (completely inconsistent) to 5 (completely consistent), of which 7 topics are reverse scoring. The higher the score, the lower the individual's fear of death and the higher the physical pain tolerance.
Time frame: baseline, 3 months
Interpersonal Needs Questionnaire
The scale consists of two subscales: frustrated sense of belonging and perceived sense of self-burdensome, with a total of 15 items. Each item is scored on a Lickert scale of 1 (completely inconsistent) to 7 (completely consistent), and 6 items are scored in reverse. The higher the score, the more frustrated the individual's sense of belonging and perceived sense of self-burdensome, and the less the interpersonal needs are met.
Time frame: baseline, 3 months
Beck Hopelessness Scale
Used to measure the degree of hopelessness that individuals feel. Hopelessness refers to the psychological state in which individuals are pessimistic about the future and think that their efforts will not bring positive results. This feeling may be related to depression, anxiety and other mental health problems. Baker's hopelessness questionnaire usually contains a series of questions, which require the subjects to answer according to their own feelings and ideas, so as to evaluate their hopelessness level;
Time frame: baseline, 3 months
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