Effectiveness of Large Language Model-Based Chatbot Among Parents of Junior High School Girls in Improving Human Papillomavirus (HPV) Vaccine Awareness, Intention and Vaccination Rates

N/ANot Yet RecruitingNCT07525245

Xiamen University18,000 enrolled

Overview

This is an interventional study targeting parents of junior high school girls. The primary objective of the study is to evaluate the effectiveness of a vaccine chatbot in improving HPV vaccination rates among parents' junior high school girls. The secondary objectives are to evaluate the effectiveness in improving vaccine awareness and vaccination intention among parents. All participants will be enrolled and randomly assigned to four groups: (1) vaccine chatbot plus scientific videos, (2) vaccine chatbot only, (3) scientific videos only, and (4) a control group (no intervention). The chatbot will provide immediate, validated answers to participants' HPV vaccine-related questions. The scientific videos will cover content related to HPV vaccine safety, efficacy, and other relevant information. The study will compare changes in HPV vaccine awareness, vaccination intention, and vaccination behavior between the intervention groups and the control group after the intervention to evaluate whether the three intervention strategies enhance HPV vaccine awareness, vaccination intention, and vaccination uptake.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

NONE

Enrollment

18,000

Conditions

HPV Vaccination Rates HPV Vaccine Awareness

Eligibility

Sex: ALLHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Parents of junior high school girls. 2. Possess an electronic device with QR code scanning capability. 3. Junior high school girls have no contraindications to HPV vaccination. 4. No mental disorders or visual/reading impairments; able to cooperate with and implement the corresponding intervention activities. 5. Have provided informed consent and are willing to participate in the study. Exclusion Criteria: \-

Outcomes

Primary Outcomes

Human papillomavirus (HPV) vaccination rates for parents' junior high school girls in all groups before and after the intervention

Whether junior high school girls get vaccinated against HPV or have an appointment for vaccination, measured by self-report and validated by vaccination information system

Time frame: Baseline and two months

Secondary Outcomes

HPV vaccine awareness for eligible parents of junior high school girls in all groups before and after the intervention

A questionnaire consisting of 11 questions related to HPV vaccines will be used to investigate the awareness of HPV vaccines.Total knowledge score is calculated based on the number of questions answered correctly by the participants and the higher scores mean a better outcome.

Time frame: Baseline and two weeks

HPV vaccination intention for eligible parents of junior high school girls in all groups before and after the intervention

Parents' willingness to vaccinate their junior high school girls, measured using a five-point Likert scale from "not willing at all" to "strongly willing"