This retrospective observational study evaluates semiological and electroclinical characteristics of psychogenic nonepileptic seizures (PNES) in adult patients who underwent video-EEG monitoring. The study aims to identify distinct semiological patterns and classify PNES events based on observable ictal features recorded during video-EEG monitoring.
Psychogenic nonepileptic seizures (PNES) are paroxysmal events that resemble epileptic seizures but are not associated with ictal epileptiform activity on electroencephalography (EEG). Video-EEG monitoring is the gold standard for diagnosis. In this retrospective observational study, video-EEG recordings and clinical data of 52 adult patients diagnosed with PNES were reviewed. Semiological features observed during recorded events were systematically evaluated and coded as binary variables. Hierarchical cluster analysis (Ward's method with squared Euclidean distance) was used to identify semiological patterns. The aim was to define clinically meaningful clusters of PNES events and to describe their demographic and clinical correlates.
Study Type
OBSERVATIONAL
Enrollment
50
Tepecik EAH
Izmir, Turkey (Türkiye)
Semiological cluster classification of PNES events
Classification of PNES events into semiological clusters (pauci-kinetic, hyperkinetic, hyperventilation-eye closure) based on ictal features identified during video-EEG monitoring.
Time frame: Baseline (retrospective video-EEG analysis)
pnes events
Eye closure during PNES events Hyperventilation during PNES events Abrupt onset of PNES events Abrupt termination of PNES events Hyperkinetic motor activity Presence or absence of excessive motor activity (e.g., thrashing movements). Tremor during PNES events Dystonic posturing Axial extension Axial immobility Pelvic thrusting Presence or absence of pelvic thrusting.
Time frame: baseline
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