This single-site, randomized, blinded, placebo-controlled study will evaluate whether 4 weeks of daily Triple Support Protein powder improves glycemic control and overall well-being in healthy women aged 30-60 years. Participants will undergo baseline testing (DXA, fasting blood, standardized meal test with 2-hour glucose and insulin sampling), complete one acute supervised dose, and then consume a daily supplement for 4 weeks. During the final 14 days, participants will wear a continuous glucose monitor. Outcomes include postprandial glucose AUC, insulin sensitivity, and body composition.
Midlife women experience hormonal changes that can impair metabolic health, sleep, and cognition. Triple plant-based protein powder includes creatine and fiber aimed at glycemic control, muscle support, and satiety. Design: 40 participants randomized (1:1) to Triple Protein Support vs. matched placebo for 4 weeks, with acute and chronic phases, weekly check-ins. Assessments: Baseline and end-of-study DXA and bloods; standardized meal tests with 2-hour glucose/insulin sampling; Analysis: Mixed-model ANOVA for primary and secondary endpoints with α=0.05.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Enrollment
40
Plant based protein + creatine + fiber
Non-caloric matched placebo
Department of Exercise and Sport Science, Applied Physiology Laboratory
Chapel Hill, North Carolina, United States
RECRUITINGChange in postprandial glucose area under the curve (AUC)
Glucose measured at 0-120 minutes post-meal; AUC by trapezoidal method.
Time frame: Glucose measured over 0-120 minutes starting post standardized meal
Change in insulin sensitivity (HOMA-IR)
Calculated from fasting glucose and insulin.
Time frame: Baseline, Week 6
Change in lean soft tissue
Lean soft tissue measured from whole body dual energy x-ray absorptiometry
Time frame: Baseline, week 6
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.