Effectiveness Analysis of a Rehabilitation Exercise Platform for Living Donor Liver Transplantation Patients

N/AEnrolling By InvitationNCT07530913

Samsung Medical Center36 enrolled

Overview

This randomized controlled study aims to evaluate the effectiveness of a digital rehabilitation exercise platform in patients undergoing living donor liver transplantation. A total of 36 adult patients who require ongoing rehabilitation after living donor liver transplantation will be recruited and randomly assigned in a 1:1 ratio to either an intervention group or a control group. The intervention group will receive a personalized exercise program delivered through a digital rehabilitation platform in addition to standard exercise education, whereas the control group will receive standard exercise education only. Physical function, body composition, quality of life, and physical activity will be assessed before surgery, at discharge, at 1 month after discharge, and at 3 months after discharge to determine whether the digital rehabilitation platform improves recovery-related outcomes during the post-transplant period.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Liver Transplantation

Interventions

Eligibility

Sex: ALLMin age: 20 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients undergoing living donor liver transplantation who require continuous rehabilitation treatment * Adults aged 20 to 65 years * Able to independently operate digital devices such as a smartphone or tablet PC * Able to perform exercises and review feedback using the digital rehabilitation platform * No significant impairment in hearing, vision, or cognitive function that would interfere with understanding audio and visual instructions provided by the platform Exclusion Criteria: * Patients with an inadequate level of consciousness or cognitive impairment making cooperation with the rehabilitation exercise program difficult * Patients who have difficulty using digital devices or cannot independently use digital-based services * Patients with severe limitations in muscle strength or range of motion, or amputation-related disability, making the exercise program difficult to perform * Patients who require restriction of movement necessary for the rehabilitation exercise program due to fracture or musculoskeletal instability * Patients with pain during upper or lower extremity movement and biomechanical instability that makes participation difficult * Patients with visual or hearing impairment that interferes with cooperation in the rehabilitation exercise program * Patients who develop medical complications or transplant rejection during study participation * Patients unable to perform physical activity because of abdominal pain

Outcomes

Primary Outcomes

6-Minute Walk Distance in meters

Six-minute walk distance will be measured using the 6-Minute Walk Test to assess functional exercise capacity and physical endurance in patients undergoing living donor liver transplantation. The reported value will be the total distance walked in meters.

Time frame: Baseline (preoperative admission), on the day of hospital discharge from the index transplantation admission, 1 month after discharge, and 3 months after discharge

Secondary Outcomes

Medical Research Council Sum Score

Overall muscle strength will be assessed using the Medical Research Council Sum Score. The reported value will be the total MRC Sum Score.